This edited volume is an invitation to redesign STEM higher education. It shows the way to active learning in diverse scenarios and provides educators, leaders and policymakers with a visionary approach to active learning and hands-on examples of how education can help students navigate complexity and unpredictability--the challenges of contemporary society. Featuring contributions from a diverse array of scholars and practitioners, this book explores: (1) Creative learning strategies; (2) Dynamic teacher-student interactions; (3) Innovative assessment methods; and (4) The design of engaging learning environments. Integrating science education with perspectives from pragmatism, science and technology studies, the humanities, art and design, this book presents a framework for understanding knowledge as an evolving, performative process. Through insightful case studies, the book emphasises agency and creativity as essential elements of learning, promoting interdisciplinary collaboration and flexible problem-solving.