The motivation for the organization of this symposium was the accumulation of evidence from many sources, both short- and long-term, that the global climate is in a state of change. Data which defy integrated explanation including temperature, ozone, methane, precipitation and other climate-related trends have presented troubling problems for atmospheric science since the 1980's. Ten papers from this symposium are presented here: (1) "Global Change and the Changing Atmosphere" (William C. Clark); (2) "Stratospheric Ozone Depletion: Global Processes" (Daniel L. Albritton); (3) "Stratospheric Ozone Depletion: Antarctic Processes" (Robert T. Watson); (4) "The Role of Halocarbons in Stratospheric Ozone Depletion" (F. Sherwood Rowland); (5) "Heterogenous Chemical Processes in Ozone Depletion" (Mario J. Molina); (6) "Free Radicals in the Earth's Atmosphere: Measurement and Interpretation" (James G. Anderson); (7) "Theoretical Projections of Stratospheric Change Due to Increasing Greenhouse Gases and Changing Ozone Concentrations" (Jerry D. Mahlman); (8) "Historical Trends in Atmospheric Methane Concentration and the Temperature Sensitivity of Methane Outgassing from Boreal and Polar Regions" (Robert C. Harriss); (9) "Global Temperature Trends" (Kevin E. Trenberth); and (10) "Use of Numerical Models to Project Greenhouse Gas-Induced Warming in Polar Regions (The Conceptual Basis Developed Over the Last Twenty Years)" (Robert E. Dickinson). A glossary of terms, agendas, and a list of participants are appended. (CW)