These proceedings contain papers of the 6th International Baltic Symposium on Science and Technology Education (BalticSTE2025) held in Šiauliai, Lithuania, June 16-19, 2025. This collection of BalticSTE25 articles presents 13 scientific articles and an introductory article on the topic of natural science and technology education. The articles cover a wide range of topics, from curriculum renewal and competency-based education to advanced methodologies, such as metacognitive strategies, application of artificial intelligence, or multimodal teaching methods. Attention is also paid to the aspects of inclusion, integration of sustainability themes, and the role of leadership in the context of educational change. The published articles were submitted by researchers from Lithuania, Slovenia, Czech Republic, Latvia, Italy, India, South Africa, France, Greece, Finland, Estonia, and the United States. Keynote speakers include Paolo Bussotti , Muammer Çalik, Katarzyna Potyrala, Stamatios Papadakis, Lukáš Richterek, and Gražina Šmitiene. This collection can serve as a valuable resource for educational researchers, educational practitioners, and policymakers seeking sound, evidence-based decisions and sustainable educational development. [Individual papers are indexed in ERIC.]