This document consists of four years (40 issues) of a newsletter devoted to computers in life science education. Titles of major articles in this collection include: (1) "Good Versus Bad Software: What Makes the Difference?" (G. Kearsly); (2) "Linkway: Hypermedia for IBM Personal Computers" (L. Kheriaty); (3) "Where's the Software: Parts 1-3" (4) "Keeping Abreast of the Literature" (5) "Course of Action: CAI Software Tool for Macintosh Course Authors" (R. Heath); (6) "Microcomputer Workstations for Human Physiology Laboratories" (J. Breckler); (7) "A Comparison of Three Graphically Oriented Simulation Environments for the Macintosh" (J. Mandel), (8) "Hypertext Options for the Educational Software Developer" (J. Frkonja); (9) "Hypertext as an Authoring Environment" (H. Modell); (10) "Making 'Unsuitable' Software Suitable" (H. Modell); (11) "Constructing a Science Center in the Age of Hypermedia" (M. Koltsky); (12) "Biology Courseware for College Freshmen: The Sequel" (C. Ralph); (13) "Adapting MS-DOS Quickbasic Programs for the Macintosh" (H. Modell); (14) "Designing Protocols for Student Laboratories" (H. Modell); (15) "Where are the Videodiscs?"; (16) "Computer Programs for Memory Tests" (I. Sipinkova and J. Zahumensky); and (16) "Developing Simulations to Help Students Learn Renal Physiology" (H. Modell). (PR)