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du Verglas, Gabrielle; And Others – Journal of Autism and Developmental Disorders, 1988
A review of research studies on the effects of fenfluramine as a pharmaceutical treatment for autistic children is presented. Fenfluramine had positive effects on the reduction of hyperactivity and stereotypic behaviors in approximately one-third of subjects. The best responders were children with the highest baseline intelligence quotients.…
Descriptors: Autism, Behavior Disorders, Drug Therapy, Hyperactivity
Peer reviewed Peer reviewed
McDougle, Christopher J.; Kresch, Laura E.; Posey, David J. – Journal of Autism and Developmental Disorders, 2000
Results from two studies indicate the nonselective serotonin reuptake inhibitor (SRI) clomipramine is more efficacious than the relatively selective norepinephrine reuptake inhibitor desipramine and placebo in children with autism. A study of the selective SRI fluvoxamine found it to be significantly better than placebo for reducing repetitive…
Descriptors: Adults, Behavior Disorders, Behavior Problems, Children