Background: Traditionally, meta-analysis of time-to-event outcomes reports a single pooled hazard ratio assuming proportional hazards (PH). For health technology assessment evaluations, hazard ratios are frequently extrapolated across a lifetime horizon. However, when treatment effects vary over time, an assumption of PH is not always valid. The…

This research aims to compare the ability and item parameter estimations of Item Response Theory according to Maximum likelihood and Bayesian approaches in different Monte Carlo simulation conditions. For this purpose, depending on the changes in the priori distribution type, sample size, test length, and logistics model, the ability and item…

Rare events meta-analyses of randomized controlled trials (RCTs) are often underpowered because the outcomes are infrequent. Real-world evidence (RWE) from non-randomized studies may provide valuable complementary evidence about the effects of rare events, and there is growing interest in including such evidence in the decision-making process.…

The performance of statistical methods is often evaluated by means of simulation studies. In case of network meta-analysis of binary data, however, simulations are not currently available for many practically relevant settings. We perform a simulation study for sparse networks of trials under between-trial heterogeneity and including multi-arm…

Meta-analyses of clinical trials targeting rare events face particular challenges when the data lack adequate numbers of events for all treatment arms. Especially when the number of studies is low, standard random-effects meta-analysis methods can lead to serious distortions because of such data sparsity. To overcome this, we suggest the use of…

It is not unusual for several tests measuring different abilities to be given in one test administration. A common practice is to estimate these abilities independently of each other, but this paper proposes a more efficient method of estimating these abilities that takes into account the correlational structure of the abilities. The method uses a…

A content analysis was conducted of three educational research journals published by the American Educational Research Association to review the quantitative and qualitative techniques used in educational research. All articles appearing in these three journals from 1988 through 1995 (total n=1,715) were considered. Research methods were…