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Peter J. Godolphin; Nadine Marlin; Chantelle Cornett; David J. Fisher; Jayne F. Tierney; Ian R. White; Ewelina Rogozinska – Research Synthesis Methods, 2024
Individual participant data (IPD) meta-analyses of randomised trials are considered a reliable way to assess participant-level treatment effect modifiers but may not make the best use of the available data. Traditionally, effect modifiers are explored one covariate at a time, which gives rise to the possibility that evidence of treatment-covariate…
Descriptors: Meta Analysis, Randomized Controlled Trials, Statistical Analysis, Participant Characteristics