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Direct linkCao, Wenhao; Siegel, Lianne; Zhou, Jincheng; Zhu, Motao; Tong, Tiejun; Chen, Yong; Chu, Haitao – Research Synthesis Methods, 2021
A reference interval provides a basis for physicians to determine whether a measurement is typical of a healthy individual. It can be interpreted as a prediction interval for a new individual from the overall population. However, a reference interval based on a single study may not be representative of the broader population. Meta-analysis can…
Descriptors: Meta Analysis, Statistical Analysis, Intervals, Computation
Hoyer, Annika; Hirt, Stefan; Kuss, Oliver – Research Synthesis Methods, 2018
Systematic reviews and meta-analyses are the cornerstones of evidence-based medicine and inform treatment, diagnosis, or prevention of individual patients as well as policy decisions in health care. Statistical methods for the meta-analysis of intervention studies are well established today. Meta-analysis for diagnostic accuracy trials has also…
Descriptors: Medicine, Evidence Based Practice, Research Methodology, Meta Analysis
