Recent advances in genomics make it possible to predict individual differences in education from polygenic scores that are person-specific aggregates of inherited DNA differences. Here, we systematically reviewed and meta-analyzed the strength of these DNA-based predictions for educational attainment (e.g., years spent in full-time education) and…

Chromosomal abnormalities are now considered a common cause of intellectual disability. With increased genetic testing, phenotyping and technological advancements, many new syndromes have been identified. This review sought to explore parental stress and adjustment in the context of rare genetic syndromes to evaluate their clinical impact. A…

Background: There is a need to systematically compare and contrast mortality predictors and disparities in people with intellectual disabilities (ID) for global prevention strategy development. Method: Bibliographic databases and grey literature were searched using systematic review methodology and the machine learning tool "Abstrackr."…

The heritability of substance dependence (SD) liability is based on polymorphisms at the genes that are likely to be related to the function of the central nervous system. We have recently shown an association between the dopamine D5 receptor gene and SD liability. We report herein a replication of this association in an independent case-control…

Reviews risk of psychosocial problems related to drinking among "grown-up" children of alcoholics. Argues that genetic predisposition is best predictor available; this may be more influential near severe end of alcoholism spectrum, may be less influential in females, and may lead to differences in symptomatology and management.…

The academic achievement of boys with fragile X syndrome and the relation between several predictive factors and academic performance are reported. Boys with fragile X syndrome displayed significant deficits in all academic skill areas. Relative strengths were observed in general knowledge, reflecting the ability to integrate experiential…

This book is a compendium of papers presented March 18-20, 1996, at the eighteenth annual Spectrum of Developmental Disabilities course. Research findings are presented that address identification, diagnosis, management, and prognosis of specific reading disability. Individual chapters include: (1) "Dyslexia: The Evolution of a Concept" (John…