The performance of statistical methods is often evaluated by means of simulation studies. In case of network meta-analysis of binary data, however, simulations are not currently available for many practically relevant settings. We perform a simulation study for sparse networks of trials under between-trial heterogeneity and including multi-arm…

Meta-analyses of clinical trials targeting rare events face particular challenges when the data lack adequate numbers of events for all treatment arms. Especially when the number of studies is low, standard random-effects meta-analysis methods can lead to serious distortions because of such data sparsity. To overcome this, we suggest the use of…

In this paper, I extend the concept of observer effect into the realm of country-level secondary data analysis. When analyzing what appear to be the same secondary data using the same methods, macro-comparative researchers arrive at different results. I argue that this is a product of idiosyncratic variation directly or indirectly produced by the…

This paper details the anticipated impact of synthetic "big" data on learning analytics (LA) infrastructures, with a particular focus on data governance, the acceleration of service development, and the benchmarking of predictive models. By reviewing two cases, one at the sector-wide level (the Jisc learning analytics architecture) and…