The COVID-19 pandemic has had a profound impact on the education sector worldwide, and on undergraduate students in particular. This Scoping Review seeks to unearth research examining the psychosocial impact of the pandemic on undergraduate students in the regions of North America, Latin America, and the Caribbean. Additionally, this review explores students' coping mechanisms as a means to guide researchers in conducting informed investigations and to allow institutions in making meaningful decisions to combat the effects of the pandemic and future disruptions. Despite the wealth of research on COVID-19, findings from this review show a notable scarcity of literature specifically focused on undergraduate students. Findings reveal a consensus among studies regarding increased stress, anxiety, and depression among undergraduate students. Coping strategies employed by students highlight possible challenges such as overuse of social media and substance use, but they also shed light on potential interventions including physical activities, emotional strategies, and social supports. Future research should focus on filling the gaps in the existing literature and assessing the efficacy of targeted interventions. By gaining a deeper understanding of undergraduate student experiences and identifying effective support mechanisms, we can enhance the overall well-being and academic success of students.