In order to propose intervention methods that can effectively improve the vocational skills of adolescents with autism spectrum disorders, meta-analysis is conducted on 16 research articles in the past twenty years focusing on single-type subjects. The intervention Tau-U effect values of related studies are calculated, and adjustment analysis is made on the subjects' characteristics, intervention types, intervention methods, intervention environment, dependent variables and the degree of matching between intervention objectives and subject characteristics. The results show that the intervention effect of vocational skills of ASD adolescents is overall significant. In terms of participant characteristics, the intervention effect of high- or medium-functioning ASD adolescents was better than that of low-functioning ASD adolescents. The analysis of intervention types showed statistically significant differences, among which the audio cueing method had the strongest intervention effect, and the frequency of mobile device teaching and behavioral skills training increased significantly. The effect of multi-component interventions is the same as that of single interventions, and it shows a good trend in the past five years and has been widely employed. Vocational skill interventions promote the employment of over 10 million persons with ASD in China, which not only helps achieve their economic independence but also is an important means to improve the social happiness index.