Outputs from living evidence syntheses projects have been used widely during the pandemic by guideline developers to form evidence-based recommendations. However, the needs of different stakeholders cannot be accommodated by solely providing pre-defined non amendable numerical summaries. Stakeholders also need to understand the data and perform…

The evolution from classical genetics to biotechnology, an area of research involving key macromolecules in living cells, is chronicled and the current state of biotechnology is described, noting related advances in computing and clinical medicine. (MSE)

The use of microelectronics and computers in medicine is reviewed, focusing on medical research; medical data collection, storage, retrieval, and manipulation; medical decision making; computed tomography; ultrasonic imaging; role in clinical laboratories; and use as adjuncts for diagnostic tests, monitors of critically-ill patients, and with the…

A line of biomedical devices based on aerospace expertise leads a sampling of spinoffs in the field of medicine. These include a National Aeronautics and Space Administration (NASA)-developed computer program used by the Centers for Disease Control, medical products research, crawling aid, portable medical system, and human tissue stimulator.…

Scientists are designing computer models of biological systems, and of compounds with complex molecules, that can be used to get answers once obtainable only by sacrificing laboratory animals. Although most programs are still under development, some are in use by industrial/pharmaceutical companies. The programs and experiments they simulate are…

Discusses the role and use of microcomputers in scientific research, from monitoring instruments to controlling experimental processes. Included are descriptions of a computer-controlled protein sequencer and gene synthesizer, and microcomputer uses in medicine, physiology, biochemistry, and geology. (JN)

An analysis of the state of medical informatics, the application of computer and information technology to biomedicine, looks at trends and concerns, including integration of traditionally distinct enterprises (clinical information systems, financial information, scholarly support activities, infrastructures); informatics career choice and…

The Grand Rapids Area Medical Education Center undertook to promote and facilitate research on the local campus of the Michigan State University College of Human Medicine through consultation on all phases of medical research. The services were offered to house officers, volunteer and paid faculty, and medical students. (MSE)