This paper and the accompanying CD-ROM disks are the outcome of a federally funded project to research and develop an interactive multimedia sign language training system for educational interpreters for students with deafness. The program consists of four 20- to 30-minute lessons on the use of non-manual grammatical markers in American Sign Language. Specific lessons are on question forms, topicalization, conditionals, and negation/assertion. The paper describes the procedures that were followed for designing, developing, and testing the interactive learning system. Features of the program include: (1) lessons provided on IBM-compatible CD-ROM disks; (2) textual instruction supplemented with video segments of fluent signers; (3) on-screen evaluation of the interpreter's understanding of how non-manual markers are being used in the video segments; (4) immediate feedback to aid the learning process; (5) video intensive lessons that present multiple models of deaf signers; (6) an interactive tutorial that explains major features and how to navigate the program; and (7) student interaction with each video by pausing, stopping or replaying the video, and by playing the video at normal or slow-motion speeds. (CR)