The Longitudinal Surveys of Australian Youth (LSAY) are a series of nationally representative surveys of young people, which follow their transitions from compulsory schooling to postschool education and into employment. The survey program is administered by the National Centre for Vocational Education Research (NCVER) on behalf of the Australian Government Department of Education, Skills and Employment. This publication presents research highlights from the past 25 years of the LSAY program, with a focus on schooling, vocational education and training (VET) in schools programs, the influences of socioeconomic status and demographics on later opportunities, and pathways taken from school into further education and the workforce. In late 2018, the National Centre for Vocational Education Research (NCVER) identified the previous research that best demonstrated the broad coverage of the LSAY data. The authors of those studies were invited to submit summaries for inclusion in this publication. A total of 14 submissions have been organised into the following six sections: (1) Research using LSAY: Reflections from Tom Karmel; (2) Socioeconomic status and family background; (3) VET in schools; (4) School experiences, maths, and expectations of enrolling in university; (5) Employment and post-school outcomes; and (6) An overview of school-to-work transitions. [The following authors summarized their research into chapters for this publication: Alison Anlezark, Jenny Chesters, Emerick Chew, Grant Cooper, David D. Curtis, Tom Karmel, Helen Law, Jung-Sook Lee, Philip Parker, Francisco Perales, Cain Polidano, Rasika Ranasinghe, Joanna Sikora, John Stanwick, Domenico Tabasso, Wojtek Tomaszewski, and Ning Xiang.]