The Leadership and Assistance for Science Education Reform (LASER) Model is a systemic approach to science learning and teaching based on five infrastructure pillars: research-based curriculum, differentiated professional development, administrative and community support, materials support, and assessment. This model uses the Science and Technology Concepts (STC) program, an inquiry-based curriculum with connections to mathematics and language arts. In August 2010, the Smithsonian Science Education Center (SSEC) received a grant of more than $25 million from the U.S. Department of Education's Investing in Innovation (i3) program for a five-year study to validate LASER model in three very diverse regions of the United States: rural North Carolina, northern New Mexico, and the Houston Independent School District (HISD). This report will provide a short description of each pillar, summarized from SSEC (Smithsonian Science Education Center) documentation, information gleaned from CREP's instruments and surveys, and general interpretations of that information.