This report looks at the uptake of General Certificate of Secondary Education (GCSE) (and IGCSE/International GCSE) subjects in England in 2017. The data for these analyses was taken from the National Pupil Database (NPD). This is a database held by the Department for Education, consisting of results for all students in all subjects in schools and colleges in England, as well as student characteristics such as age and gender. For analyses here, the Key Stage 4 (KS4) extract of the NPD was used, consisting of all students who were at the end of KS4 in 2017 (i.e., in year 11). Uptake in this report is defined as the percentage of these students taking a GCSE in the subject, and includes exams taken by these students in previous years. Uptake of GCSEs in this report is presented by different student classifications: gender, school type, attainment level, school gender and deprivation level. In the tables in this report, the numbers of students in each of the classifications are presented. [For the 2016 report, see ED621984.]