This article presents the authors' rejoinder to the comments of Howard Bloom, Derek Neal, and Mike Seltzer on their article. Their commentary focused foremost on the advantages and disadvantages of using Options A, B, or C in using instrumental variables in multisite trials. Of interest are the quantities one can estimate and test in each case,…

The concept of treatment integrity cuts across a diversity of fields involved with providing treatments or interventions to individuals. In medical treatments, the concept of "treatment compliance" or "treatment adherence" is an important and problematic issue. In the field of nutrition, the concept of "dietary adherence" is important for…

Research-based technologies for solving problems currently exist but are not being widely implemented. Although user variables, program effectiveness, and political considerations have been documented as correlates of implementation, general non-implementation of the technology still exists, due to a lack of methods. A technology of dissemination…

Discussion of the value of diffusion of innovation theory for predicting the implementation of end-user online searching highlights a study of Canadian health professionals who were early adopters of end-user searching. User perceptions are emphasized, and the use of diffusion of innovation theory in information science research is recommended.…