Enzymes are nature's catalysts, mediating chemical processes in living systems. The study of enzyme function and mechanism includes defining the maximum catalytic rate and affinity for substrate/s (among other factors), referred to as enzyme kinetics. Enzyme kinetics is a staple of biochemistry curricula and other disciplines, from molecular and…

In this essay, the author tries to look forward into the 21st century to divine three things: (i) What skills will researchers in the future need to solve the most pressing problems? (ii) What are some of the most likely candidates to be those problems? and (iii) What are some current areas of research that seem mined out and should not distract…

Four empirical laws of bibliometrics--anomalous number, Lotka's, Zipf's, and Bradford's--together with Laplace's "law of succession" and de Solla Price's cumulative advantage distribution are shown to be almost identical. A simple model shows that the frequency forms conform with inverse square law over appropriate interval. (Fifteen…

Discusses aspects of the syntax and semantics of film, and presents a scenario for the use of film by intelligent computer assisted instruction (ICAI) systems. An outline of a representation language for educational films on videodisc is presented, and an appendix provides conceptual graphs that explain notations used in examples. (Author/LRW)

Discusses the use and interpretation of multiple regression analysis with computer programs and presents a flow chart of the process. A general explanation of the flow chart is provided, followed by an example showing the development of a linear equation which could be used in estimating manufacturing overhead cost. (Author/LRW)

Discusses current use of psychological theory in software science and reviews recent developments in cognitive psychology relevant to programing (human information processing, expert-novice differences). Critique of Maurice Halstead's model of cognitive aspects of programing and a structured data flow perspective (control flow and data flow…

Explored are various aspects of drawing graphs on surfaces. The Euler's formula, Kuratowski's theorem and the drawing of graphs in the plane with as few crossings as possible are discussed. Some applications including embedding of graphs and coloring of maps are included. (YP)

Presents a diagram for figuring the value of time into an individual's labor-supply decisions and the time intensiveness of the individual's consumption patterns. Seeks to make the integration of differing time values with leisure income choices more understandable for students. (DK)

MINDS (Multiple Intelligent Node Document Servers) is a distributed system of knowledge-based query engines for efficiently retrieving multimedia documents in an office environment of distributed workstations. By learning document distribution patterns and user interests and preferences during system usage, it customizes document retrievals for…

This article discusses tools developed to aid the systems analysis process (program evaluation and review technique, Gantt charts, organizational charts, decision tables, flowcharts, hierarchy plus input-process-output). Similarities and differences among techniques, library applications of analysis, structured systems analysis, and the data flow…

Zipfian laws for frequency distributions of word pairs and longer phrases are derived from text sample analysis. From crossing of Zipfian curves, it is deduced that number of multi-word phrases that occur frequently in text is surprisingly small, of same order of magnitude as number of individual word-types. (8 references) (EJS)

A broad range of well-structured problems--embracing forms of diagnosis, catalog selection, and skeletal planning--are solved in expert computer systems by the method of heuristic classification. These programs have a characteristic inference structure that systematically relates data to a pre-enumerated set of solutions by abstraction, heuristic…

This paper reports on applications of quality tools, developed for industrial settings, to educational management and instruction at three technical education centers. The necessary data were collected by the centers as they prepared for registration to the International Standards Organization Quality Assurance Standards. Application was made of…

Details the 1989 funding proposals for research and development. Describes trends in federal spending. Discusses proportions of funding for the National Science Foundation, the Department of Defense, and other basic research agencies. Includes tables that detail money spent and proposed for many research agencies. (CW)

Discusses conclusions based on results of two Brown University research projects aimed at understanding social and educational significance of computing in higher education: 1984 university-wide survey of students, faculty, and staff, and a 1985 survey of incoming freshmen. The conclusions discussed relate to computer use, experience, attitudes,…