Enzymes are nature's catalysts, mediating chemical processes in living systems. The study of enzyme function and mechanism includes defining the maximum catalytic rate and affinity for substrate/s (among other factors), referred to as enzyme kinetics. Enzyme kinetics is a staple of biochemistry curricula and other disciplines, from molecular and…

This article seeks to provide researchers and practitioners in laboratory education, particularly those involved in the curriculum design and implementation of teaching laboratories at university level, with a conceptual framework and a working model for an integrated assessment of learning domains, by attending to a more holistic approach to…

Describes the necking of polymer sheets that occurs when they are stretched. Discusses the effect and the mechanisms of necking. Lists four references. (YP)

Discusses the role of dogs in research, considering their use in studies related to: behavior; aging; anesthesia; gastrointestinal surgery; the brain; organ transplants; radiobiology; trauma and shock; arterial diseases; hemophelia; ophthalmology; diabetes; nutrition; cancer; lupus; cyclic neutropenia; thyroiditis; hepatitis; skeletal system,…

Discusses issues and the public's concerns related to using laboratory animals for research purposes. Indicates that several perceptions (such as recognizing that the public's attitudes toward respect for animal life are no more irrational than many broader attitudes toward the sacredness of life) characterize the most responsible of recent…

The Grignard reagent used in the laboratory synthesis of organic compounds is the product resulting from the reaction of an alkyl or aryl halide with elemental magnesium. Describes the structure, formation, and some reactions of the reagent. (YP)

Reports an experiment for examining protein-ligand binding using the enzyme carbonic anhydrase. Describes the experimental procedures consisting of the syntheses of an azosulfonamide and its complex formation with carbonic anhydrase. (YP)

Describes experiments used during recent history to explain the nature of the quantum world. Explains the essential elements of experiments using polarized light and magnetic flux. Illustrates differences between classical theories in physics and quantum theory. Shows how experiments in the microscopic and macroscopic world appear to support…

Discusses the characteristics and development of a computer simulation laboratory for educational administration research at the University of Wisconsin at Madison, and reviews an experimental study performed at the laboratory on stress in decision-making. Explores how simulations provide researchers access to experimental conditions unavailable…

Examines the extent to which issues related to animal experimentation are in conflict and proposes choices that might least comprise them. These issues include animal well-being, human well-being, self-interest of science, scientific validity and responsibility, progress in biomedical and behavioral science, and the future quality of medical care.…

Provides information appropriate for introductory lectures on photoelectric effects in membranes. Describes the apparatus and supplies required for laboratory exercises. Outlines typical laboratory exercises. Identifies the chromophores known to induce photoelectric effects. Concludes that this topic can provide useful subjects for undergraduate…

Describes a general purpose microcomputer-based system designed to support small-scale experimentation in the physical sciences in student laboratories. System requirements, teacher reactions, and educational implications are discussed; design criteria are established; and examples are given of the system's application to some simple experiments.…

Discusses general construction principles for miniaturized laboratory glassware. Describes a prototype experimental kit that allows the carrying out of all standard laboratory operations and discusses a trial use of the equipment with students 16- to 17-years-old. (CW)

Reviews research on the purpose and effectiveness of laboratory activities. Discusses epistemology, problem solving, cooperative learning, student involvement, assessment, and teachers as researchers. (YP)

Describes the style of design of computer simulations developed by Computer Assisted Teaching Unit at Queen Mary College with reference to user interface, input and initialization, input data vetting, effective display screen use, graphical results presentation, and need for hard copy. Procedures and problems relating to academic involvement are…