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Direct linkBurgess, Nancy K.; Sweeten, Thayne L.; McMahon, William M.; Fujinami, Robert S. – Journal of Autism and Developmental Disorders, 2006
One of the most consistent biological findings in autism is elevated whole blood serotonin (5-HT) levels found in about 1/3 of cases. Immune abnormalities are also commonly observed in this disorder. Given 5-HT's role as an immunomodulator, possible connections between 5-HT and immune abnormalities in autism are explored in this review. Areas of…
Descriptors: Autism, Diseases, Neurological Impairments, Disease Incidence
Carr, Edward G.; Owen-DeSchryver, Jamie S. – Journal of Autism and Developmental Disorders, 2007
There is growing interest in the role that physical illness and pain might play in exacerbating problem behavior in individuals with developmental disabilities. Assessment of these factors, however, is often difficult since many individuals have minimal verbal communication skills. In response to this difficulty, we developed a sequential method…
Descriptors: Verbal Communication, Intervention, Developmental Disabilities, Communication Skills
Sweeten, Thayne L.; Posey, David J.; McDougle, Christopher J. – Journal of Autism and Developmental Disorders, 2004
Previous research has identified a relationship between autistic disorder (autism) and specific congenital infections. Three cases of congenital or perinatal cytomegalovirus (CMV) infection occurring in association with autism are described. Hypothetical mechanisms relating congenital infection, such as CMV, to the development of autism are…
Descriptors: Etiology, Autism, Children, Microbiology
