Dopamine participates in encoding memories and could either encode rewarding/aversive value of unconditioned stimuli or act as a novelty signal triggering contextual learning. Here we show that intraperitoneal injection of the dopamine D1/5R antagonist SCH23390 impairs contextual fear conditioning and tone-shock association, while intrahippocampal…

During associative retrieval, the brain reinstates neural representations that were present during encoding. The human medial temporal lobe (MTL), with its subregions hippocampus (HC), perirhinal cortex (PRC), and parahippocampal cortex (PHC), plays a central role in neural reinstatement. Previous studies have given compelling evidence for…

Memory palaces are effective tools for learning vast amounts of information in a canonical order using mnemonics. However, our review of the literature revealed a lack of implementation and user study of memory palace in Virtual Reality (VR) for neuroscience education. VR technology enables us to build highly interactive virtual learning spaces…

Current education paradigms were informed by the classical Newtonian worldview of brain functioning in which the mind is simply the physical activity of the brain, and our thoughts cannot have any effect upon the physical world. However, researchers in the field of quantum mechanics found that the outcomes of certain subatomic experiments are…

Conditioned fear memories that are context-specific shortly after conditioning generalize over time. We exposed rats to a context reminder 30 d after conditioning, which served to reinstate context-specificity, and investigated how this reminder alters retrieval-induced activity in the hippocampus and anterior cingulate cortex (aCC) relative to a…

The relations between the developing mind and developing brain are explored. We outline a theory of intellectual development postulating that the mind comprises four systems of processes (domain-specific, attention and working memory, reasoning, and cognizance) developing in four cycles (episodic, realistic, rule-based, and principle-based…

Ten years ago, researchers using event-related brain potentials (ERPs) to study language comprehension were puzzled by what looked like a "Semantic Illusion": Semantically anomalous, but structurally well-formed sentences did not affect the N400 component--traditionally taken to reflect semantic integration--but instead produced a P600…

We briefly discuss memory types and three modern principles of neuroscience: 1) Protein growth at the synapse, 2) the three-brain theory, and 3) the interplay of the hippocampus, the neocortex, and the prefrontal cortex. To illustrate the potential of this perspective, four applications of these principles are provided.

Recognition memory deficits, even after short delays, are sometimes observed following hippocampal damage. One hypothesis links the hippocampus with processes in updating contextual memory representation. Here, we used fornix transection, which partially disconnects the hippocampal system, and compares the performance of fornix-transected monkeys…

This paper presents an account of current literature on the topic of music and memory, supplemented by qualitative research in the form of interviews with seniors who are living with dementia. Music is a strong memory trigger, often linked with emotion, and stored in parts of the brain that, for most people, still function after other memories…

Knowledge tracing is a popular and successful approach to modeling student learning. In this paper we investigate whether the addition of neuroimaging observations to a knowledge tracing model enables accurate prediction of memory performance in held-out data. We propose a Hidden Markov Model of memory acquisition related to Bayesian Knowledge…

The goal of this article is to make the case for a radical exemplar account of child language acquisition, under which unwitnessed forms are produced and comprehended by on-the-fly analogy across multiple stored exemplars, weighted by their degree of similarity to the target with regard to the task at hand. Across the domains of (1) word meanings,…

Reversing characters (digits and letters) when writing, and complete mirror writing, raise one of the oldest and most mysterious questions in developmental and educational psychology: Why do five-year-old children write symbols (e.g., [reversed E] for E) they have neither learnt nor seen? Attempts to draw up a complete explanatory theory of…

This article proposes a theoretical foundation and practical strategies for incorporating pedagogical songs and corresponding gestures into the language classroom. Music and movement are connected to verbal memory, which is a key component of language learning. Music and language are processed in the same areas of the brain, and recent empirical…

One of the recommended approaches in instructional design methods is to optimize the value of working memory capacity and avoid cognitive overload. Educational neuroscience offers novel processes and methodologies to analyze cognitive load based on physiological measures. Observing psychophysiological changes when they occur in response to the…