When students think of evolution, they might imagine T. rex, or perhaps an abiotic scene of sizzling electrical storms and harsh reducing atmospheres, an Earth that looks like a lunar landscape. Natural selection automatically elicits responses that include "survival of the fittest," and "descent with modification," and with…

Due to its distinct phenotype and relatively simple inheritance pattern, the phenylthiocarbamide (PTC) loci is frequently utilized in teaching laboratories to demonstrate genetic concepts such as Mendelian inheritance and population genetics. We have developed a next-generation sequencing and bioinformatics approach to analyze the PTC gene locus…

Case studies are valuable tools for instruction but are often limited to a single topic and a single class period. Courses such as evolution that synthesize multiple concepts around a common theme, however, can use a single case study type project that extends over the entire semester to develop and link core concepts. A central theme in…

Understanding redox reactions in biochemistry requires a clear grasp of three definitions: electron exchange, oxidation number, and oxygen atom insertion. Here, the electrochemical cell is explained for redox-active ions, introducing a new comparison between the measurement of midpoint potential and the measurement of initial velocity for enzymes.…

Two-dimensional nuclear magnetic resonance (2D NMR) techniques are regularly used for the determination of RNA structures. In an effort to introduce advanced level students who are generally not acquainted with or exposed to these techniques, this work, which has been designed as a practicum, utilizes a combination of 2D NMR techniques to help…

The real time PCR (qPCR) method provides a powerful method to assess levels of particular species of DNA. When combined with reverse transcription (RT-qPCR) it is the predominate technique to measure expression of gene transcripts. While this approach is very powerful, particular care must be taken in the design of the primers to facilitate…

A set of core ideas in the life sciences revolve around genetics, variation, and inheritance. While the "Next Generation Science Standards" (NGSS; NGSS Lead States 2013) emphasize teaching and learning about these concepts across K-12 grades, it is critical for early learners to begin to develop understanding of them. By the end of fifth…

Is it possible to teach biology without mentioning evolution? The answer is yes, but it is not possible for students to understand biology without the evolutionary context on which the meaning and intellectual value of biological concepts depend. Meaningful learning of evolution requires (1) that the students incorporate new knowledge into a…

For many students, their science education up to the age of 16 is their only formal introduction to genetics. They live in an age where the results of genomic studies will have increasing importance for their health and well-being. This article uses Piaget's conceptions of concrete and formal thinking as tools for considering the conceptual…

A lesson plan is a design problem for a teacher. The desired solution to this problem is to design an instructional process that can guide students in constructing an understanding of scientific concepts through their own thinking. This article demonstrates a practical approach to designing an effective lesson plan. The approach has five phases:…

Demonstration of a colorimetric approach for nucleic acid detection represents an attractive educational experiment for chemistry undergraduate students in the time of coronavirus pandemic. Herein, a rapid and vivid detection method that visualizes the presence of a specific DNA sequence is described. The plasmon resonance of gold nanoparticles…

Protein synthesis, involving such abstract concepts as "DNA," "RNA," "transcription," and "translation," is one of many biological processes too small to be seen by the naked eye. This combination of scientific jargon and sub-microscopic elements can make biology seem overwhelming to any student--but…

This article describes a self-guided, story-like game with creative drawing for grades 3-5 that teaches the evolution concepts of adaptation, natural selection, ecosystem dynamics, inheritance, and mutation following the "Next Generation Science Standards" ("NGSS"). Drawing reinforces concepts through emphasis on students'…

The research completed by the authors into the teaching and learning of evolution and inheritance (2014 to 2018) seeks to understand the demands made by the revised National Curriculum in England (DfE, 2015) and to offer support. The commitment of the authors to applied research assumes more useful outcomes are likely when studies are conducted…

Statistical methods are indispensable to the practice of science. But statistical hypothesis testing can seem daunting, with P-values, null hypotheses, and the concept of statistical significance. This article explains the concepts associated with statistical hypothesis testing using the story of "the lady tasting tea," then walks the…