A symmetry activity using student-built models was developed in line with faculty-developed pedagogical goals and a collaborative learning framework. The activity took place in a 3-h laboratory portion of an upper-division inorganic chemistry course. It required students to identify symmetry elements for seven molecules using common 2D…

In an effort to improve student learning, authentic research experiences have been incorporated into introductory laboratory courses as a means to teach students scientific inquiry and engage them in the scientific process. Here, we describe the development and implementation of a novel undergraduate research-based laboratory course for first-year…

In this laboratory experiment, students apply a mass-based approach to determine the Henry's law constant for CO[subscript 2] using a small bottle of a diet carbonated beverage. The calculations are challenging; therefore, team-based learning is encouraged. Our students reported values of 0.033 ± 0.003 mol/(L[middle dot]atm) at room temperature…

The Internet of Things (IoT) is a network of objects that can exchange data with other devices also connected to the Internet. One of the most common consumer examples of IoT is home automation, as a variety of smart devices, including doorbells, lightbulbs, thermostats, and refrigerators are now available which users can control remotely using…

A green laboratory experiment has been developed in which students perform an aqueous oxidation/cycloaddition reaction to convert salicyl alcohol into a pentacyclic diepoxydione that is readily isolated by filtration. Drawing on their knowledge of periodate-mediated 1,2-diol cleavage, students propose a mechanism for the oxidation of salicyl…

A method for the synthesis of flufenamic acid, a nonstereoidal anti-inflammatory drug (NSAID) of the anthranilate family (fenams), is described as an experiment for the upper-division undergraduate organic chemistry laboratory. The key step is the formation of the diarylamine moiety of flufenamic acid by a novel reaction consisting of the coupling…

A discovery-based undergraduate organic chemistry lab experiment has been developed in which students establish the diastereoselectivity of hydride reduction of the a-chiral ketone (±)-benzoin isopropyl ether to erythro and threo diastereomeric alcohols by two different reducing agents. Students achieve this goal by working collaboratively and…

The ability to visualize chemical processes can be an asset in a teaching laboratory. Despite the advances in laboratory technology, apparatuses used in the teaching of simple thermodynamics concepts, such as exothermic/endothermic reactions, historically remain unchanged and can benefit from a fresh perspective. The recent incorporation of…

According to national labor market information study, access to talent is the greatest business challenge Canadian biotech companies are facing. We, therefore, developed, implemented, and assessed a pharma industry-inspired, medicinal research laboratory module in an experiential capstone biotechnology laboratory course. This involves developing a…

In order to introduce the concept of covalent organic frameworks (COFs), an important class of predictable crystalline porous polymers, an integrated laboratory experiment for advanced organic chemistry students is reported. The importance of these kind of polymers and their multiple applications are presented as a part of key concepts in polymer…

A multifaceted experiment, accessible to students either in an introductory organic chemistry course or in a more advanced laboratory setting, is described for investigating the addition of dichlorocarbene to E- and Z-[beta]-methylstyrenes. The innovative exercise, which integrates elements of synthesis, mechanisms, instrumental analysis,…

Due to the COVID-19 pandemic, social distancing restrictions are in place in most public settings, and the undergraduate laboratory is no exception. In order to accommodate social distancing requirements, many laboratory exercises are being redeployed in an online format, which deprives students of experiential learning opportunities in a real…

A new laboratory experiment investigating the ternary phase equilibrium of water-propan-2-ol-sodium chloride with one-, two-, and three-phase regions has been developed. Observations of the type and number of phases of a series of mixtures of the three components were made, and the results are then used in a systematic way to more finely choose…

An escape-room-game activity was introduced to foster team building and collaborative learning in a laboratory-experiment setting. The students were placed in a laboratory with clues and puzzles that required the students to use a sequence of analytical instruments in the laboratory in order to escape. The instruments utilized included a UV-vis…

Polychlorinated biphenyls (PCBs) are a family of synthetic chemicals consisting of carbon, hydrogen, and chlorine atoms. PCBs have been produced commercially since 1929 in hundreds of industrial applications. Their continued production in the United States was phased out in the late 1970s, and strict disposal guidelines were regulated as adverse…