This laboratory experiment offers a research-style experience designed for senior undergraduate students in a multidisciplinary laboratory setting. The experiment focuses on the synthesis, characterization, and application of a cation-exchange membrane made of COF-SO[subscript 3]Na/PAN for ion separation. By participating in this practical…

Enzymes provide attractive targets for drug development. Quantitative analysis of enzyme reactions can lead to rational drug discovery. For undergraduates majoring in biochemistry or pharmacy and engaged in drug discovery-related work, it is essential to acquire a comprehensive understanding of enzyme kinetics, including experimental methods and…

This report outlines an approach for preparing 5-color 3D printed plastic models of molecular orbitals and electron density surfaces using a hobby-grade 3D printer. Instructions are provided for preparing 3D orbital and electron density surface (EDS) models using solid or mesh representations in ground state and transition state structures. We…

The COVID-19 pandemic has significantly affected teaching processes worldwide, particularly in laboratory-intensive courses. To adapt, online experiments have been implemented globally. In response, educators at the Department of Chemistry, Chulalongkorn University, developed a Lab@Home chemistry experiment for their general chemistry lab course…

Hydrogen is a sustainable and climate-friendly storage for renewable energies and can directly be generated from sunlight, e.g., by photocatalytic water splitting. This article presents the photocatalytic hydrogen evolution using LED irradiation of an aqueous ZnS particle dispersion with Na[subscript 2]S and Na[subscript 2]SO[subscript 3] as…

Interdisciplinary experiments within chemistry are very important for the improvements in the overall quality of the education received by students. In this work, we describe an interdisciplinary experiment that was successfully completed by undergraduate students. This training integrates multiple disciplines including natural product medicinal…

In the past decade, C-H functionalization has been a very active topic of research in both academia and industry. When a H atom is replaced by an aryl (or heteroaryl) group, the transformation is termed "direct arylation". This approach to the formation of key (hetero)aryl-(hetero)aryl bonds is complementary to traditional methods, such…

Electrophoresis is integral to analytical and biochemistry experiences in undergraduate education; however, fundamental principles of the method are often taught in upper-level laboratories through hands-on experiences. A laboratory activity is reported that teaches the concepts of electrophoretic mobility and electroosmotic flow. A single…

Few laboratory exercises exist that introduce undergraduate students to both the concepts and instrumentation used in rotational spectroscopy. Because of this gap in undergraduate laboratory training, a teaching laboratory for the pure rotational spectroscopy of benzonitrile has been developed and reported. Owing to benzonitrile's recent discovery…

Acid-base titration laboratories are perennially offered to general chemistry students in preparation for summative assessments of their hands-on and quantitative skills in the field. Here, we present a guided inquiry-based activity focused on total titratable acidity (TTA) as alternative to standard "cookbook" titration laboratory work.…

This activity introduces droplet-based millifluidics and the usage of aqueous droplets as independent chemical microreactors for reaction-kinetics studies. Students build their own droplet generators from common macroscopic glassware and connecting parts to create trains of millimeter-sized droplets in which a redox reaction takes place. The…

An easily constructed and inexpensive polarimeter with an optical rotation angle resolution of about 0.5° is presented. It is made from small pieces of polarizing film, 2 LEDs, a protractor, and a few wires, all held in place with plastic interlocking toy bricks, such as Lego bricks. The instrument was used to demonstrate the optical rotation of…

This communicaton shares with the chemistry education community the rubrics used to evaluate student videos associated with using a pipet, using a buret, and making a solution in a volumetric flask that were part of a digital badging project. The rubrics were used across multiple general chemistry courses, hundreds of teaching assistants, and…

A multioutcome, guided inquiry-based liquid--liquid extraction (LLE) experiment has been designed for introductory organic chemistry. Multiple outcomes were established by identifying a series of red and blue dyes that are (1) soluble in organic solvent, (2) soluble in aqueous solution, or (3) soluble in either the organic or aqueous layers by…

Students entering into a quantitative analysis course often struggle with connecting theoretical aspects of concepts from lecture to hands-on applications in the laboratory setting. A one-semester quantitative analysis course was redesigned to integrate active learning with a project-based curriculum that incorporated structured review of…