Suppose "X" and "Y" are binary exposure and outcome variables, and we have full knowledge of the distribution of "Y," given application of "X." We are interested in assessing whether an outcome in some case is due to the exposure. This "probability of causation" is of interest in comparative…

In behavioral research, interest is often in examining the degree to which the effect of an independent variable X on an outcome Y is mediated by an intermediary or mediator variable M. This article illustrates how generalized estimating equations (GEE) modeling can be used to estimate the indirect or mediated effect, defined as the amount by…