A symmetry activity using student-built models was developed in line with faculty-developed pedagogical goals and a collaborative learning framework. The activity took place in a 3-h laboratory portion of an upper-division inorganic chemistry course. It required students to identify symmetry elements for seven molecules using common 2D…

The analysis of functional groups in organic compounds and inorganic ions in salts is a laboratory experiment that forms an inevitable part of the undergraduate chemistry curriculum in the science field all over the world. With this experiment, the student learns the testing techniques for the chemicals and gets a true sense of the importance of…

The acid-catalyzed dehydration of regioisomeric methylcyclohexanols is a classic organic chemistry experiment featured in a variety of laboratory textbooks and literature. The mechanistic details of this reaction have received an inconsistent and occasionally inaccurate treatment, wherein the reaction has been described as a mix of E1, E2-like,…

Enzymes are nature's catalysts, mediating chemical processes in living systems. The study of enzyme function and mechanism includes defining the maximum catalytic rate and affinity for substrate/s (among other factors), referred to as enzyme kinetics. Enzyme kinetics is a staple of biochemistry curricula and other disciplines, from molecular and…

Two misconceptions about the mechanism of image formation in the human eye are common among students and even in textbooks and other teaching materials. The first attributes all refraction to the eye lens; the second treats the eye as a pinhole camera. To reduce these persistent conceptions of students, a series of simple experiments is presented…

A version of the classic rotationally resolved infrared (IR) spectrum of a diatomic molecule experiment has been developed using the POGIL framework to more fully engage students in the collection, modeling, analysis, and interpretation of the data. An analysis of the experimental protocol reveals that the POGIL approach actively engages students…

Novice chemists often struggle with the highly visual nature of some chemistry topics. To make visually demanding concepts, such as isomerism and stereochemistry, more accessible to students, chemistry instructors have long recommended the use of molecular model kits as visual aids. However, studies pertaining to student model usage have shown…

Progress is made in science by constructing many models (possibly of different complexities), testing them against measurements, and determining which of them explain the data the best. It is my observation, however, that in many introductory physics labs we provide students with the materials and methods to verify the "correct" model of…

Laboratory experiments that offer interdisciplinary experiences for students are appealing and are increasingly popular additions to undergraduate chemistry curricula. Students can capitalize on their knowledge of multiple areas of chemistry while working through an application, and this fosters the development of progressive problem-solving…

Most biochemical transformations involve more than one substrate. Bisubstrate enzymes catalyze multiple chemical reactions in living systems and include members of the transferase, oxidoreductase, and ligase enzyme classes. Working knowledge of bisubstrate enzyme kinetic models is thus of clear importance to the practicing biochemist. However,…

This paper was inspired by the work of a previous contributor on the subject of modelling plague epidemiology by comparing it to the physics of series radioactive decay, RC transients, and fluid dynamics. An Arduino-based experiment to illustrate the fluid-dynamical case is described. Attention is drawn to important differences between systems…

The CRISPR/Cas9 system is a powerful tool for gene editing and it has become increasingly important for biology students to understand this emerging technique. Most CRISPR laboratory teaching modules use complex metazoan systems or mammalian cell culture which can be expensive. Here, we present a lab module that engages students in learning the…

Teaching simple circuits and Ohm's law to students in the introductory classroom has been extensively investigated through the common practice of using incandescent light bulbs to help students develop a conceptual foundation before moving on to quantitative analysis. However, the bulb filaments' resistance has a large temperature dependence,…

Two wires exit a black box that has three exposed light bulbs connected together in an unknown configuration. The task for students is to determine the circuit configuration without opening the box. In the activity described in this paper, we navigate students through the process of making models, developing and conducting experiments that can…

A semester-long hypothesis-driven laboratory project for second-semester biochemistry has been developed. Working independently, students propose a hypothesis about the role of one amino acid residue in the active site of 5,10-methenyltetrahydrofolate synthetase (MTHFS). They then test this hypothesis by site-directed mutagenesis of a plasmid…