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Konstantina Chalkou; Tasnim Hamza; Pascal Benkert; Jens Kuhle; Chiara Zecca; Gabrielle Simoneau; Fabio Pellegrini; Andrea Manca; Matthias Egger; Georgia Salanti – Research Synthesis Methods, 2024
Some patients benefit from a treatment while others may do so less or do not benefit at all. We have previously developed a two-stage network meta-regression prediction model that synthesized randomized trials and evaluates how treatment effects vary across patient characteristics. In this article, we extended this model to combine different…
Descriptors: Medical Research, Outcomes of Treatment, Risk, Randomized Controlled Trials
Siegel, Lianne; Chu, Haitao – Research Synthesis Methods, 2023
Reference intervals, or reference ranges, aid medical decision-making by containing a pre-specified proportion (e.g., 95%) of the measurements in a representative healthy population. We recently proposed three approaches for estimating a reference interval from a meta-analysis based on a random effects model: a frequentist approach, a Bayesian…
Descriptors: Bayesian Statistics, Meta Analysis, Intervals, Decision Making
Efthimiou, Orestis; White, Ian R. – Research Synthesis Methods, 2020
Standard models for network meta-analysis simultaneously estimate multiple relative treatment effects. In practice, after estimation, these multiple estimates usually pass through a formal or informal selection procedure, eg, when researchers draw conclusions about the effects of the best performing treatment in the network. In this paper, we…
Descriptors: Models, Meta Analysis, Network Analysis, Simulation
Noma, Hisashi; Gosho, Masahiko; Ishii, Ryota; Oba, Koji; Furukawa, Toshi A. – Research Synthesis Methods, 2020
Network meta-analysis has been gaining prominence as an evidence synthesis method that enables the comprehensive synthesis and simultaneous comparison of multiple treatments. In many network meta-analyses, some of the constituent studies may have markedly different characteristics from the others, and may be influential enough to change the…
Descriptors: Networks, Meta Analysis, Evidence, Comparative Analysis
Felege, Christopher; Hahn, Emily; Hunter, Cheryl – Journal of Research Practice, 2016
Translational research originated in the medical field during the 1990s to describe taking discovery based research through the steps of applying it to clinical research and patient-oriented care. This model is implicitly linear, depicting the flow of information from researchers' bench, to a clinical trial bedside, to a primary care physician's…
Descriptors: Educational Research, Research and Development, Research Reports, Research Utilization
Burnette, Margaret H. – portal: Libraries and the Academy, 2015
The increasing interdisciplinarity of scientific research creates both challenges and opportunities for librarians. The liaison model may be inadequate for supporting campus research that represents multiple disciplines and geographically dispersed departments. The identification of units, researchers, and projects is a first step in planning and…
Descriptors: Interdisciplinary Approach, Biomedicine, Medical Research, Scientific Research
Aroian, Karen J.; Robertson, Patricia; Allred, Kelly; Andrews, Diane; Waldrop, Julee – Journal of Research Administration, 2012
In the current era of limited funding, researchers need strategic alliances to launch or sustain programs of research to significantly impact the nation's health. This article presents a collaborative model, the Scholar Award Model, which is based on a strategic alliance between a College of Nursing in a research-intensive university and a…
Descriptors: Child Health, Partnerships in Education, Hospitals, Research Universities
Afshartous, David; Preston, Richard A. – Journal of Statistics Education, 2011
We consider the effect on estimation of simultaneous variable centering and interaction effects in linear regression. We technically define, review, and amplify many of the statistical issues for interaction models with centering in order to create a useful and compact reference for teachers, students, and applied researchers. In addition, we…
Descriptors: Interaction, Regression (Statistics), Computation, Research Methodology
Cutler, David M.; Meara, Ellen; Richards-Shubik, Seth – Journal of Human Resources, 2012
We develop a model of induced innovation that applies to medical research. Our model yields three empirical predictions. First, initial death rates and subsequent research effort should be positively correlated. Second, research effort should be associated with more rapid mortality declines. Third, as a byproduct of targeting the most common…
Descriptors: Evidence, Innovation, Medical Services, Infants
Buckley, Frank – Down Syndrome Research and Practice, 2008
Animal models are extensively used in genetics, neuroscience and biomedical research. Recent studies illustrate the usefulness and the challenges of research utilising genetically engineered mice to explore the developmental biology of Down syndrome. These studies highlight many of the issues at the centre of what we understand about Down…
Descriptors: Quality of Life, Down Syndrome, Genetics, Biomedicine

Croen, Lila G.; And Others – Journal of Medical Education, 1986
A 2-month program for third-year students at Yeshiva's Albert Einstein College of Medicine that provides a model for integrating basic sciences and clinical training is described. It demonstrates the importance of lifelong learning in a field that constantly changes. (Author/MLW)
Descriptors: Course Descriptions, Course Evaluation, Curriculum Development, Higher Education

Walther, James H.; Speisser, Nancy – Issues in Science & Technology Librarianship, 1997
Presents a model for medical reference source instruction. Focuses on identifying the potential audiences; conducting user and information assessments; creating and delivering models of training; and future goals. Includes a list of Internet healthcare sites. (AEF)
Descriptors: Information Retrieval, Information Seeking, Information Sources, Internet
National Inst. of Child Health and Human Development (NIH), Bethesda, MD. – 1993
This research plan describes a framework for defining and developing the field of rehabilitation sciences and research opportunities for the National Center for Medical Rehabilitation Research (NCMRR) and other agencies funding medical rehabilitation research. The plan addresses the needs of both persons who are involved in habilitation and in…
Descriptors: Classification, Disabilities, Federal Programs, Financial Support
Moran, Barbara B. – 1997
With the support of a planning grant from the National Library of Medicine, the University of North Carolina at Chapel Hill (UNC) School of Information and Library Science (SILS), in collaboration with the UNC Health Sciences Library and the Program in Medical Informatics, evaluated five curricular models designed to improve education for health…
Descriptors: Curriculum Development, Curriculum Evaluation, Educational Objectives, Educational Quality