Substitution reactions of alcohols are some of the simplest experiments performed in undergraduate organic chemistry laboratory settings. However, the use of gas chromatography (GC) as an analytical tool for these reactions can be at times laborious and time-consuming. In this work, 1-pentanol, 2-pentanol, 3-pentanol, and 2-methyl-2-butanol were…

Within the eukaryotic cell, the actin cytoskeleton is a crucial structural framework that maintains cellular form, regulates cell movement and division, and facilitates the internal transportation of proteins and organelles. External cues induce alterations in the actin cytoskeleton primarily through the activation of Rho GTPases, which then bind…

This work describes a complete laboratory experiment that involves the synthesis of a ruthenium complex [Ru(p-cym)(NHC)Cl[subscript 2]] (NHC = N-heterocyclic carbene) and its use as a catalyst for the coupling of hydrosilanes and alcohols. The hydrogen gas produced in the reaction is measured using an inverted buret to trap the gas which allows…

Highlighting the interdisciplinary nature of research, we present a series of experiments for undergraduate lab courses that teach the principles of preparative ion exchange chromatography and flame emission spectroscopy. Through these inquiry-based experiments, the students learn about experimental design and instrument limitations, naturally…

Flame Emission Spectroscopy (FES) is a powerful analytical technique widely used for identifying and quantifying elements in various samples. In this laboratory experiment, undergraduate students were introduced to FES and its significance in analytical chemistry. The experiment aimed to provide students with hands-on experience in constructing…

A drug discovery project has been successfully implemented in an advanced undergraduate organic chemistry laboratory. In the laboratory, a five-step synthetic sequence is used to prepare five analogues of 13-phenyl-1-tridecanol. These compounds are key precursors in the synthesis of 2-oxo-14-phenyltetradecanes. This class of compounds, isolated…

The aldol condensation reaction is one of the many synthesis reactions carried out in second semester organic chemistry laboratories. This reaction was integrated into a novel experiment requiring students to synthesize dibenzalace tone derivatives using the crossed-aldol condensation by reacting different types of benzaldehyde derivatives with…

A traditional laboratory course with the primary learning outcome of improving students' theoretical knowledge has received much criticism over the years due to the lack of evidence that these goals have achieved. We report our efforts to redesign a traditional first-year organic and inorganic (also known as synthetic) laboratory course from…

This article describes a straightforward approach to deliver an enzyme assay and kinetics laboratory via online delivery methods in the time of COVID-19.

A class of 18 students attending the last year of an Italian high school was divided into groups and performed the extraction of pigments contained in hibiscus tea. Each group worked at a different temperature and carried out multiple extractions using distilled water as a solvent. By means of UV-vis spectroscopy it was possible to determine the…

Interdisciplinary experiments within chemistry are very important for the improvements in the overall quality of the education received by students. In this work, we describe an interdisciplinary experiment that was successfully completed by undergraduate students. This training integrates multiple disciplines including natural product medicinal…

This paper introduces hands-on curricular modules integrated with research in atmospheric ice nucleation, which is an important phenomenon potentially influencing global climate change. The primary goal of this work is to promote meaningful laboratory exercises to enhance the competence of students in the fields of science, technology,…

By focusing on food and a pervasive contaminant, this experiment engages student interest and effort while providing essential instruction and experience. As institutions are challenged by existing and emerging budgetary constraints, this experiment offers a determination approach employing commonly available instrumentation, the graphite furnace…

A revised version of a traditional physical chemistry laboratory experiment has been developed to enhance student discussion in the laboratory and to improve students' connections between physical chemistry concepts and real molecular systems. In this experiment, students explore the keto-enol tautomerization of 2,4-pentanedione. However, unlike…

Enzymes are widely applied in different industries, like pharmaceutical, food, biofuel, and waste valorization. However, the enzyme operating conditions are very limited. So, in most industrial processes, enzymes are not efficient, due to the use of harsh conditions, like organic solvents, extreme pH, and temperature. Immobilization arises as a…