Within the eukaryotic cell, the actin cytoskeleton is a crucial structural framework that maintains cellular form, regulates cell movement and division, and facilitates the internal transportation of proteins and organelles. External cues induce alterations in the actin cytoskeleton primarily through the activation of Rho GTPases, which then bind…

A new project-based laboratory (PJBL) was developed for general chemistry students to tackle the steps involved in chemical water quality analysis using an accessible, real-world hydrologic system (the lakes of the Lower Grand Coulee, Washington). This PJBL was developed in a joint general chemistry and environmental geology course by a…

This article describes the implementation of a student-generated open educational resource project into a majors' organic chemistry laboratory. This scaffolded semester-long project was organized into six phases and designed to promote the goals of teaching students about both green chemistry and real-life applications of the reactions covered in…

An integrated lab-lecture project, known as the mini research project, was developed for a medicinal chemistry course for nonscience majors. In the lecture component of this project, students choose a plant essential oil with documented biological activity and prepare a literature review describing the importance, history, and current use of the…

Many laboratory courses consist of short and seemingly unconnected individual laboratory exercises. To increase the course consistency, relevance, and student engagement, we have developed a research-inspired and project-based module, "From Gene to Structure and Function". This 2.5-week full-day biochemistry and structural biology module…

In fall 2020, the Physics Department was tasked with coming up for a plan for optics, our one credit lab course. Because of the continued COVID-19 pandemic, our institution planned to offer a fully online fall semester, with no students residing on campus. The college announced the plan 5 weeks prior to the start of the semester. This paper will…

One way that STEM (science, technology, engineering, and math) initiatives are being utilized is to encourage schools and teachers to integrate key science-based concepts into daily instruction. The reason is simple: it is more than just an instructional improvement or curricular enhancement; it is a research-based strategy that addresses the…

School lockers are an essential part of secondary school life and students have been using them for decades. It is unlikely the design has changed since they were used by their grandparents. Although lockers have not changed, school definitely has. Are school lockers something that also need to be changed? A design challenge is an open-ended…

Students entering into a quantitative analysis course often struggle with connecting theoretical aspects of concepts from lecture to hands-on applications in the laboratory setting. A one-semester quantitative analysis course was redesigned to integrate active learning with a project-based curriculum that incorporated structured review of…

To enhance critical thinking and problem-solving skills, a project-based learning (PBL) approach for "Instrumental Techniques" courses in undergraduate physical chemistry was specifically developed for a pharmacy bachelor degree program. The starting point of this PBL was an open-ended question that is close to the student scientist's…

This work describes a 10-week laboratory project studying wild-type and mutant bacterial alkaline phosphatase, in which students purify, quantitate, and perform kinetic assays on wild-type and selected mutants of the enzyme. Students also perform plasmid DNA purification, digestion, and gel analysis. In addition to simply learning important…

This paper describes pedagogical efforts implemented to promote significant learning in a computational chemistry course. The taxonomy of significant learning advanced by Fink (2013) is used as a framework to discuss the results. Fink identifies six categories of learning: foundational, application, integration, human dimension, caring, and…

We have developed a multiweek laboratory project in which students isolate myoglobin and characterize its structure, function, and redox state. The important laboratory techniques covered in this project include size-exclusion chromatography, electrophoresis, spectrophotometric titration, and FTIR spectroscopy. Regarding protein structure,…

Student engagement during the development of a three-dimensional visual aid or teaching model can vary for a number of reasons. Some students report that they are not "creative" or "good at art," often as an excuse to justify less professional outcomes. Student engagement can be low when using traditional methods to produce a…

Renee Clary and James Wandersee implemented the Stratigraphy and Data Interpretation Project described in this article when they recognized that some students were having difficulties constructing appropriate graphics and interpreting their constructed graphics for an earlier mathematics-science project in their classrooms. They also previously…