Plant-derived natural products are an important source of potential medicines and continue to have a major impact on the drug discovery process. Natural product discovery assignments provide an opportunity to present various experimental techniques to undergraduate students in introductory medicinal chemistry. This assignment was developed to…

The Wiggers diagram showing simultaneous events of the cardiac cycle in composite graphs is one of the most intimidating figures students encounter in their study of physiology. This paper describes a discovery learning activity that walks students through the construction of the Wiggers diagram by focusing on the core concepts of blood flow down…

Single-type, 8-fold-grooved, commercially accessible interlocking disks (ILDs) have been used for modeling of complex polyhedral and reticular topologies with relevance to inorganic and hybrid materials. The assembly of complex topologies relies on the preparation of secondary building units (SBUs), which exhibit different connectivity than that…

This article focuses on a sequence of learning experiences designed to raise children's awareness about weaving using yarn, which is one aspect of fibre and production technologies. The technologies context of the fibre production allows children to learn about the chemistry concepts related to the materials. An explicit focus on the properties…

In this guided-inquiry lesson, students were tasked with determining the efficacy of an at-home drinking water filter at removing lead (Pb) from tap water using graphite furnace atomic absorption spectroscopy by determining the concentration of lead before and after filtration. The lesson was structured to allow students to choose and perform…

Course-based undergraduate research experiences (CUREs) integrate authentic research into undergraduate chemistry laboratories, introducing students to research while simultaneously reinforcing fundamental concepts. Despite their ubiquitous nature in bioanalytical research, few CUREs have been published applying the fundamental techniques of…

The so-called Diet Coke and Mentos experiment is initiated by dropping Mentos candies into a bottle of Diet Coke or other carbonated beverage. This causes the beverage to rapidly degas, causing foam to stream out of the bottle. Simple application of the gas laws leads to the straightforward prediction that ejection of greater foam volume is…

By bringing everyday phenomena into the classroom, teachers can more readily engage students in authentic scientific inquiry. When working with young children, the best phenomena are those that students can directly experience and investigate. Meaningful phenomena can be identified by watching children at play, listening to the conversations they…

This modular, open-framework capstone course delves deeply into the synthesis, separation, and characterization of chiral molecules while teaching critical thinking and writing skills in a research-like setting within a fertile area for discovery. This course has evolved over 30 years and has been in its present form for 5 years at the time of…

Mastery of core chemistry content is a degree requirement for several STEM majors. Gatekeeper courses, like general and physical chemistry, have a history of weeding out struggling students, and often underrepresented groups underperform. While gatekeeper courses ensure students are prepared for STEM degrees, it is essential they do not create…

At first glance, science and art seem as likely companions as oil and water. Is there more to mixing them up than mere metaphor and a messy floor? In this article, Tom Pringle shares some ideas for powering up the classroom by turning STEM into STEAM by dipping the paintbrush of art into the pot of science. In both art and science pupils can…

An undergraduate experiment for the organic laboratory is described that utilizes microwave heating to prepare 5- substituted 1H-tetrazole derivatives through a (3 + 2) cycloaddition between aryl nitriles and sodium azide. The reaction mixture is analyzed by thin layer chromatography. The products are purified through an acid-base extraction and…

In this article we propose that educational game design should work to create games as objects-to-think-with--games that engage players in the exploration of and experimentation with personally interesting questions around domain-relevant representations. We argue that this design focuses on developing tools and interactions that the player can…

A demonstration is described of electrophoretic separation of carmine and sunset yellow with a paper-based device. The channel in the paper device was fabricated by hand with a wax pen. Electrophoretic separation of carmine and sunset yellow was achieved within a few minutes by applying potential on the channel using a simple and inexpensive power…

A laboratory experiment for teaching protein separation and detection in an undergraduate biochemistry laboratory course is described. This experiment, performed in two, 4 h laboratory periods, incorporates guided inquiry principles to introduce students to the concepts behind and difficulties of protein purification. After using size-exclusion…