This article describes our efforts to screen and enrol clinical trial participants conscientiously in the COVID-19 pandemic setting. We present the standard screening and enrolment process prior to, and our process of adapting to, the pandemic. Our goal was to develop a way to screen and enrol people for clinical trials that was both equitable and…

The randomized control trial (RCT) is the primary experimental design in education research due to its strong internal validity for causal inference. However, in situations where RCTs are not feasible or ethical, quasi-experiments are alternatives to establish causal inference. This paper serves as an introduction to several quasi-experimental…

Stem cell therapy, a cutting-edge technology, aims to replace damaged cells with healthy ones. Stem cells possess the remarkable ability to multiply and differentiate into various cell types, making them ideal candidates for regenerative medicine. This therapy holds promise for treating a wide range of conditions and injuries. In this review, I…

This report summarizes student enrollment during the 2020-2021 school year for the cohort of students in the 2019-2020 prekindergarten partnership between Austin Independent School District, United Way for Greater Austin, and participating child development centers. Demographic information and academic performance for beginning-of-year are also…

Play in early childhood environments is critical to the social development of all children, including those with disabilities. Children with autism often experience delays in the development of play skills and may especially struggle with social play with peers. Thus, strategies to support social play in inclusive preschool settings are needed.…

This Perspective builds on a related RAND Corporation report that describes the implementation of Findhelp at four North Carolina community colleges in 2021 and 2022. Findhelp is an online tool to connect students to resources in their communities to help meet their basic nonacademic needs. The North Carolina Community College System, with support…

Group design research studies can provide evidence to draw conclusions about "what works," "for whom," and "under what conditions" in special education. The quality indicators introduced by Gersten and colleagues (2005) have contributed to increased rigor in group design research, which has provided substantial…

Randomization of large number of participants to different treatment groups is often not a feasible or preferable way to answer questions of immediate interest to professional practice. Single case designs (SCDs) are a class of research designs that are experimental in nature but require only a few participants, all of whom receive the…

A common motivation for adding control variables to statistical models is to reduce the potential for spurious findings when analyzing non-experimental data and to thereby allow for more reliable causal inferences. However, as I show here, unless "all" potential confounding factors are included in an analysis (which is unlikely to be…

An aspect of a study is considered a confounding factor if it is not possible to tell whether the difference in outcomes is due to the intervention, the confounding factor, or both. In What Works Clearinghouse (WWC) study reviews, certified reviewers look for a specific type of confounding factor: those that occur when a component of the study…

In school settings, nurses lead efforts to improve the student health and well-being to support academic success. Nurses are guided by evidenced-based practice and data to inform care decisions. The randomized controlled trial (RCT) is considered the gold standard of scientific rigor for clinical trials. RCTs are critical to the development of…

By creating and analyzing matched samples, researchers can simplify their analyses to include fewer covariate variables, relying less on model assumptions, and thus generating results that may be easier to report and interpret. When two groups essentially "look" the same, it is easier to explore their differences and make comparisons…

The What Works Clearinghouse (WWC) uses the term "baseline equivalence" when determining if the intervention group (those that received the intervention of interest) and the comparison group (those that did not receive the intervention) had characteristics that were similar enough ("equivalent") at the start of the study (at…

"Attrition" is the loss of sample during the course of a study. It occurs when individuals initially randomly assigned in a study are not included when researchers examine the outcome of interest. Attrition is a common issue in education research, and it occurs for many reasons. The What Works Clearinghouse (WWC) is an initiative of the…

Demonstration of experimental control is considered a hallmark of high-quality single-case research design (SCRD). Studies that fail to demonstrate experimental control may not be published because researchers are unwilling to submit these papers for publication and journals are unlikely to publish negative results (i.e., the file drawer effect).…