The study of use of the drug fenfluramine with four autistic children (7-20 years old) indicated no significant side effects, a reduction in some deviant behaviors, and an improvement in activity level/attention span. (Author/DB)

The oral opiate, naltrexone, was used in a double-blind placebo-controlled study with two young profoundly mentally adults who exhibited intractable self-injurious behavior. No measurable effects on the self-injurious behavior were observed. (Author/DB)

A double-blind placebo-controlled study was conducted to assess the effects of intermittent drug therapy on stereotyped and collateral behaviors of six profoundly mentally retarded, institutionalized, adult males. Despite a marked reduction in medication, there was no general change of clinical significance in any of the behaviors. (Author/DB)

Evaluation of a 16-session group intervention for reducing inappropriately expressed anger (as aggression) in 25 individuals with intellectual disabilities found a reduction in expressed anger and measured levels of depression. Reductions in expressed anger were maintained at 6 and 12 months follow-up, although scores on the depression scale…

A study of 16 individuals with severe and profound mental retardation and 16 direct-care staff from a residential facility investigated changes in interactive behaviors between clients and staff. Results found that, after staff training, there were slight positive increases in staff interactions with the residents. No consistent change was found…

A multi-faceted training package for inappropriate social behavior was evaluated with five children with mild mental retardation and attention deficit hyperactivity disorder in a residential program. Residents were individually trained in self-management skills with video feedback. Direct-care staff also received training. Although staff increased…