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Turner, Simon Lee; Korevaar, Elizabeth; Cumpston, Miranda S.; Kanukula, Raju; Forbes, Andrew B.; McKenzie, Joanne E. – Research Synthesis Methods, 2023
Interrupted time series (ITS) studies are frequently used to examine the impact of population-level interventions or exposures. Systematic reviews with meta-analyses including ITS designs may inform public health and policy decision-making. Re-analysis of ITS may be required for inclusion in meta-analysis. While publications of ITS rarely provide…
Descriptors: Quasiexperimental Design, Graphs, Accuracy, Computation
Doleman, Brett; Freeman, Suzanne C.; Lund, Jonathan N.; Williams, John P.; Sutton, Alex J. – Research Synthesis Methods, 2020
This study aimed to determine for continuous outcomes dependent on baseline risk, whether funnel plot asymmetry may be due to statistical artefact rather than publication bias and evaluate a novel test to resolve this. Firstly, we conducted assessment for publication bias in nine meta-analyses of postoperative analgesics (344 trials with 25 348…
Descriptors: Outcomes of Treatment, Risk, Publications, Bias
Polanin, Joshua R.; Pigott, Terri D. – Research Synthesis Methods, 2015
Meta-analysis multiplicity, the concept of conducting multiple tests of statistical significance within one review, is an underdeveloped literature. We address this issue by considering how Type I errors can impact meta-analytic results, suggest how statistical power may be affected through the use of multiplicity corrections, and propose how…
Descriptors: Meta Analysis, Statistical Significance, Error Patterns, Research Methodology