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Taeyeop Lee; Hyeji Lee; Soowhee Kim; Kee Jeong Park; Joon-Yong An; Hyo-Won Kim – Journal of Autism and Developmental Disorders, 2024
The aim of this study was to examine genetic variations underlying the early neurodevelopmental outcome of developmental disabilities (DDs). The study cohort consisted of 191 children with DDs. Diagnosis was assessed at baseline and at the index age (72-84 months). Exome sequencing was conducted and putative risk variants were identified.…
Descriptors: Developmental Disabilities, Children, Genetics, Risk
Rachel A. Gordon; Sandra W. Russ; Anastasia Dimitropoulos – Journal of Developmental and Physical Disabilities, 2024
Background: Children with Prader-Willi Syndrome (PWS) display impaired pretend play abilities, reflective of broader social-cognitive challenges. Pretend play interventions for children with PWS demonstrate preliminary efficacy for improving cognitive and affective processes in play. It is unknown which specific intervention strategies, such as…
Descriptors: Children, Preadolescents, Genetic Disorders, Play
García-Alcón, Alicia; González-Peñas, Javier; Weckx, Elisa; Penzol, M. J.; Gurriarán, Xaquín; Costas, Javier; Díaz-Caneja, Covadonga M.; Moreno, Carmen; Hernández, Patricia; Arango, Celso; Parellada, Mara – Journal of Autism and Developmental Disorders, 2023
Whether there is a relationship between oxytocin (OXT) use in labor and the risk of autism (ASD), and the nature of such relationship, is unclear. By integrating genetic and clinical data in a sample of 176 ASD participants, we tested the hypothesis that OXT is a marker for abnormal prenatal development which leads to impairments in the process of…
Descriptors: Genetics, Autism Spectrum Disorders, Prenatal Influences, Prenatal Care
Womack, Sean R.; Beam, Christopher R.; Davis, Deborah Winders; Finkel, Deborah; Turkheimer, Eric – Developmental Psychology, 2022
Twins regularly score nearly a standard deviation below the population mean on standardized measures of cognitive development in infancy but recover to the population mean by early childhood, making rapid gains through the toddler years. To date, only polynomial growth models have been fit to model cognitive recovery across childhood, limiting the…
Descriptors: Twins, Cognitive Ability, Genetics, Environmental Influences
Dai Zhang; Yanghui Xie; Longsheng Wang; Ke Zhou – npj Science of Learning, 2024
Arithmetic ability is critical for daily life, academic achievement, career development, and future economic success. Individual differences in arithmetic skills among children and adolescents are related to variations in brain structures. Most existing studies have used hypothesis-driven region of interest analysis. To identify distributed brain…
Descriptors: Mathematics Skills, Prediction, Arithmetic, Academic Achievement
Farran, Emily K.; Purser, Harry R. M.; Jarrold, Christopher; Thomas, Michael S. C.; Scerif, Gaia; Stojanovik, Vesna; Van Herwegen, Jo – Developmental Science, 2024
Williams syndrome (WS) is a rare genetic syndrome. As with all rare syndromes, obtaining adequately powered sample sizes is a challenge. Here we present legacy data from seven UK labs, enabling the characterisation of cross-sectional and longitudinal developmental trajectories of verbal and non-verbal development in the largest sample of…
Descriptors: Genetic Disorders, Verbal Communication, Nonverbal Communication, Communication Skills
Joshua Anbar; Nicole Matthews; Stephen James; Afzal Ariff; Karen Pierce; Christopher J. Smith – Journal of Autism and Developmental Disorders, 2024
Few studies have examined differences in autism spectrum disorder (ASD) phenotype between children from multiplex and simplex families at the time of diagnosis. The present study used an age- and gender-matched, community-based sample (n = 105) from the southwestern United States to examine differences in ASD symptom severity, cognitive…
Descriptors: Autism Spectrum Disorders, Symptoms (Individual Disorders), Genetic Disorders, Severity (of Disability)
Bruno Sauce; John Wiedenhoeft; Nicholas Judd; Torkel Klingberg – npj Science of Learning, 2021
The interplay of genetic and environmental factors behind cognitive development has preoccupied multiple fields of science and sparked heated debates over the decades. Here we tested the hypothesis that developmental genes rely heavily on cognitive challenges - as opposed to natural maturation. Starting with a polygenic score (cogPGS) that…
Descriptors: Foreign Countries, Children, Adolescents, Short Term Memory
Lai, Philip T.; Ng, Rowena; Bellugi, Ursula – International Journal of Developmental Disabilities, 2022
The majority of the research examining children with Autism Spectrum Disorder (ASD) and Williams Syndrome (WS) focus on the social domain while few have examined cognitive style and emotionality. Accordingly, this current study assessed the day-to-day cognitive and behavioral functioning of school-age children with ASD, WS, and neurotypical…
Descriptors: Autism Spectrum Disorders, Genetic Disorders, Children, Cognitive Ability
Mairon, Noam; Abramson, Lior; Knafo-Noam, Ariel; Perry, Anat; Nahum, Mor – Developmental Psychology, 2023
Empathy and executive functions (EFs) are multimodal constructs that enable individuals to cope with their environment. Both abilities develop throughout childhood and are known to contribute to social behavior and academic performance in young adolescents. Notably, mentalizing and EF activate shared frontotemporal brain areas, which in previous…
Descriptors: Empathy, Correlation, Twins, Longitudinal Studies
Racionero-Plaza, Sandra; Flecha, Ramón; Carbonell, Sara; Rodríguez-Oramas, Alfonso – Qualitative Research in Education, 2023
Scientific literature about neuromyths has proliferated in the last few years. However, there is a gap of knowledge around neuroedumyths. While neuromyths are based on hoaxes about the brain, neuroedumyths use neuroscientific concepts but state consequences for education that are false. This article presents, for the first time, research about…
Descriptors: Equal Education, Access to Education, Neurosciences, Brain Hemisphere Functions
Taupiac, Emmanuelle; Lacombe, Didier; Thiébaut, Eric; Van-Gils, Julien; Michel, Grégory; Fergelot, Patricia; Adrien, Jean-Louis – Journal of Intellectual & Developmental Disability, 2021
Background: Rubinstein-Taybi syndrome (RSTS) is a multiple congenital anomaly syndrome characterised by several typical somatic characteristics and by developmental disabilities with various degrees of severity. Focusing on children with RSTS, the aim of this study was to describe their psychomotor, cognitive, and socio-emotional developmental…
Descriptors: Genetic Disorders, Congenital Impairments, Severe Intellectual Disability, Children
Amoako, Annika Nina; Hare, Dougal Julian – Journal of Applied Research in Intellectual Disabilities, 2020
Background: Research into Rett syndrome has included various medical interventions. Non-medical interventions are relatively under-researched. Recent technological communication intervention advances have contributed to the evidence base in Rett syndrome. Method: The Embase, PsycINFO and MEDLINE were systematically searched for peer-reviewed…
Descriptors: Genetic Disorders, Intervention, Interpersonal Communication, Music
Andres, Erin M.; Earnest, Kathleen Kelsey; Smith, Shelley D.; Rice, Mabel L.; Raza, Muhammad Hashim – Journal of Speech, Language, and Hearing Research, 2020
Purpose: Specific language impairment (SLI) is characterized by a delay in language acquisition despite a lack of other developmental delays or hearing loss. Genetics of SLI is poorly understood. The purpose of this study is to identify SLI genetic loci through family-based linkage mapping. Method: We performed genome-wide parametric linkage…
Descriptors: Genetics, Language Impairments, Developmental Delays, Hearing Impairments
Moriguchi, Yusuke; Shinohara, Ikuko – Developmental Science, 2018
Low executive function (EF) during early childhood is a major risk factor for developmental delay, academic failure, and social withdrawal. Susceptible genes may affect the molecular and biological mechanisms underpinning EF. More specifically, genes associated with the regulation of prefrontal dopamine may modulate the response of prefrontal…
Descriptors: Young Children, Executive Function, Brain Hemisphere Functions, Genetics