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Grazioplene, Rachael G.; DeYoung, Colin G.; Rogosch, Fred A.; Cicchetti, Dante – Journal of Child Psychology and Psychiatry, 2013
Background: The differential susceptibility hypothesis states that some genetic variants that confer risk in adverse environments are beneficial in normal or nurturing environments. The cholinergic system is promising as a source of susceptibility genes because of its involvement in learning and neural plasticity. The cholinergic receptor gene…
Descriptors: Genetics, Personality Traits, Child Abuse, Environmental Influences

Hudziak, James J.; Derks, Eske M.; Althoff, Robert R.; Copeland, William; Boomsma, Dorret I. – Journal of the American Academy of Child and Adolescent Psychiatry, 2005
Objective: To estimate the genetic and environmental contributions to oppositional defiant behavior (ODB) from mother, father, and teacher report using the Conners Revised Short Forms in a large twin sample. Method: ODB data were collected from 1,595 mothers, 1,114 fathers, and 793 teachers of 7-year-old twin pairs from the Netherlands Twin…
Descriptors: Foreign Countries, Psychiatry, Twins, Mothers
Grizenko, Natalie; Kovacina, Bojan; Amor, Leila Ben; Schwartz, George; Ter-Stepanian, Marina; Joober, Ridha – Journal of the American Academy of Child and Adolescent Psychiatry, 2006
Objective: To compare the pattern of familial aggregation of psychopathology in children who are good responders (GR) to methylphenidate (MPH) versus those who are poor responders (PR). Method: A total of 118 clinically referred children ages 6 to 12 years, diagnosed with ADHD participated in a double-blind, placebo-controlled, randomized 2-week…
Descriptors: Psychopathology, Personality, Personality Problems, Hyperactivity