Multiple choice results are inherently probabilistic outcomes, as correct responses reflect a combination of knowledge and guessing, while incorrect responses additionally reflect blunder, a confidently committed mistake. To objectively resolve knowledge from responses in an MC test structure, we evaluated probabilistic models that explicitly…

This study aimed at designing instructional material named Biotechnology Instruction Module (BIM) which is enriched with active learning methods to enhance the 8th grade students' learning of the topic. The development of the teaching materials proceeded within the stages of the ADDIE instructional design model. The final form of the instructional…

In this narrative, a detailed model for trichotomously positive [or "Tripositive"] "Nanobiogenic Technology™" (as "dynamic nanobiotechnology") is presented via research-based case studies. The author implemented the Biosmart Nanobiogenic Technology™(or "Biosmart Nanobiotechnology") designed to create a…

The use of a molecular viewer to visualize proteins has become more prevalent in high schools in recent years. We relied on the foundations of two theoretical frameworks to analyze questions in two learning tasks designed for 10th- to 12th-grade biotechnology majors that make use of Jmol. The two theoretical frameworks were: (i) classification of…

In complex interfirm exchange relationships like alliances, firms that invest in relation-specific assets are likely to devise governance mechanisms, most prominently hierarchical control, to safeguard against various exchange hazards. However, if investing in relation-specific assets leads the focal alliance firm to discover new opportunities…

The aim of the present study is to explore pre-service elementary teachers' evaluations of the evidence and models and their positions on a socio-scientific topic, namely genetically modified organisms (GMOs), after evaluating them through Model Evidence Link (MEL) diagrams. The findings of this study show that the participants mostly constructed…

The BIOSEL (Biotechnology Series Learning) model is a learning model that provides opportunities for students to assemble learning through a conceptual description of the coherent and precise steps of Biotechnology implementation. The purpose of this research was to analyze validity and practicality of the BIOSEL model to improve the concept…

The molecular structure of living organisms and the complex interactions amongst its components are the basis for the diversity observed at the macroscopic level. Proteins and nucleic acids are some of the major molecular components, and play a key role in several biological functions, such as those of development and evolution. This article…

Students frequently expressed difficulty in understanding the molecular mechanisms involved in chromosomal recombination. Therefore, we explored alternative methods for presenting the two concepts of the double-strand break model: Holliday junction and heteroduplex formation, and Holliday junction resolution. In addition to a lecture and…

Data mining is known to have a potential for predicting user performance. However, there are few studies that explore its potential for predicting student behavior in a procedural training environment. This paper presents a collective student model, which is built from past student logs. These logs are first grouped into clusters. Then, an…

The objective of the present work was to implement a teaching system useful in modeling and simulation of biotechnological processes. The interactive system is based on applications developed using 20-sim modeling and simulation software environment. A procedure for the simulation of bioprocesses modeled by bond graphs is proposed and simulators…

We evaluate the effects of state-provided financial incentives for biotech companies, which are part of a growing trend of placed-based policies designed to spur innovation clusters. We estimate that the adoption of subsidies for biotech employers by a state raises the number of star biotech scientists in that state by about 15 percent over a…

Embedded assessments, tasks within the context of instruction, can serve as important tools for improving teaching and learning. In this article, we report on the assessment design principles and a nine-step development model that guided the construction of innovative embedded assessments. Using multiple sources of data--expert reviews, a…

Knowledge spillovers from universities and other public research institutions (PRIs) are viewed as essential for innovation. Previous studies examining the impact of such spillovers have been confined to the West, and there are no comparable studies using empirical data from Japan that explore the relationship between spillovers from PRIs and…

Purpose: Proteomic methodologies offer promise in elucidating the systemwide cellular and molecular processes that characterize normal and diseased thyroarytenoid (TA) muscle. This study examined methodological issues central to the application of 2-dimensional sodium dodecyl sulfate polyacrylamide gel electrophoresis (2D SDS-PAGE) to the study of…