Chemical reactions that mimic the function of ATP hydrolysis in biochemistry are of current interest in nonequilibrium systems chemistry. The formation of transient bonds from these reactions can drive molecular machines or generate materials with time-dependent properties. While the behavior of these systems can be complicated, the underlying…

A laboratory experiment was designed to introduce the practical application of biocatalysis in Bachelor and Master courses in biotechnology and medicinal chemistry, respectively. To this aim, the lipase from "Candida rugosa" was characterized (protein concentration and activity), immobilized on a carrier (by hydrophobic adsorption), and…

The subject of pharmaceutical research has traditionally focused on drugs with systemic effects. However, contemporary approaches aspire to achieve targeted drug delivery, with the aim of combatting infections with a precise immune response. Active substances are encapsulated in nanoparticles, transported through the body, and selectively released…

Student engagement in evidence-based argumentation plays a central role in science education. These skills can be developed when identifying organic molecules from the spectroscopic data. Molecular structural analysis fosters deep procedural knowledge, as it involves (i) flexibly applying a set of procedures to extract information from spectra,…

The electrolysis of water to produce hydrogen is a critical step in many green chemistry processes. The key to the efficiency of water electrolysis is the synthesis of an appropriate electrocatalyst. Three-dimensional (3D) printing is an increasingly important part of many industrial processes. In this study, we propose an efficient laboratory…

The urea cycle disorder drug glycerol phenylbutyrate (Ravicti) is presently one of the most expensive medications in the United States, with annual costs estimated at $800,000 as of 2023. An expedient synthesis of this orphan drug was successfully adapted for the undergraduate organic chemistry laboratory. Activation of 4-phenylbutyric acid with…

As the 21st century progresses, we are increasingly reminded of the importance of and need for green chemistry, which also leads to the corresponding need for green chemistry education. The UC Berkeley Department of Chemistry developed a green chemistry laboratory curriculum-the "General Chemistry Green Curriculum" ("GC[superscript…

Herein we describe an accessible and safe at-home experiment to separate lycopene from tomatoes via liquid-liquid extraction. As a qualitative experiment, it is a canonically elementary instance for high school students to digest the conception of miscibility, immiscibility, and density difference of the two solvents. This experiment was performed…

The COVID-19 pandemic was an unprecedented event that, out of necessity, drastically changed the way undergraduate chemistry courses were taught. With the cancellation of in-person classes, laboratory experiences were delayed and/or moved to the virtual space, the latter keeping the general framework of the laboratory experiment but removing the…

A simple demonstration adaptable to classroom conditions is presented, which involves the preparation of raffle tickets using filter paper and the solution of selected fluorophores. With an appropriate dilution, the text written on the tickets is not visible to the naked eye; however, it becomes readable once put under a UV lamp. Besides being a…

A renewed experimental procedure for the unknown carbonyl experiment has been developed using hydrazone synthesis, thin layer chromatography (TLC) analysis, and melting point determination to differentiate between structurally similar ketones and aldehydes in undergraduate organic chemistry practical courses. Benzaldehyde, p-tolualdehyde,…

In primary organic chemistry, students learn about the dehydration of ethanol to ethylene with concentrated sulfuric acid. Similar reactions(the dehydration of alcohols) exist in nature. For example, various alkenes with aromas are synthesized from linalool, a monoterpene tertiary alcohol. In this laboratory experiment, we report experiments…

Integrating new synthetic methods and experimental techniques from the latest research reports into undergraduate laboratory experiments is of great significance, as it enables students to learn the cutting-edge technology of organic chemistry and cultivates their experimental skills and innovative thinking. In this study, an experiment on their…

Digital badges are credentials earned via a digital presentation to demonstrate the mastery of a technique. They have been utilized in General Chemistry laboratory courses as an assessment tool and to document students' development of a skill. A digital badge assignment was developed for thin layer chromatography (TLC) and integrated into a…

Teacher educators have focused on designing learning environments 'for' rather than 'with' teacher candidates. However, a co-design collaboration with teacher candidates has been recently suggested as a critical feature for effective teacher education programs. In this study, a co-design team, including preservice science teachers (PSTs) as…