This study used the Interprofessional Attitudes Scale (IPAS) to examine attitudes of pharmacy and nursing students before and after an interprofessional education activity at a health science center campus. Results were analyzed using a matched pairs design to detect changes in attitudes from pre- to post-survey. Findings showed statistically significant changes with small effect sizes on seven items, with six moving in the desired direction and one moving in a direction not desired. Descriptive data indicated a possible need for intervention regarding prejudices and assumptions about other disciplines within health care professions.