Anaerobic metabolism is recruited in vertebrates under conditions of intense exercise or lowered environmental oxygen availability (hypoxia), typically resulting in the accumulation of lactate in blood and tissues. Lactate will be cleared over time after the reoxygenation of tissues, eventually returning to control levels. Here, we present a…

In a recent influential report by the National Research Council, the role of the laboratory was introduced as follows: "Science courses and the laboratories associated with them should cultivate the ability of students to think independently. They should provide students with exposure to realistic scientific questions and highlight those aspects…

The strong-inference protocol puts into action the important concepts in Platt's often-assigned, classic paper on the strong-inference method (10). Yet, perhaps because students are frequently performing experiments with known outcomes, the protocols they write as undergraduates are usually little more than step-by-step instructions for performing…