Although unrecognized for his scientific achievements during his life, Gregor Mendel pioneered our modern understanding of the gene, work that shaped the field of genetics and advances in biology and medicine. The field that he set in motion 200 years ago lies at the center of current ethical debates about the future of humanity, the limits of…

Case studies are valuable tools for instruction but are often limited to a single topic and a single class period. Courses such as evolution that synthesize multiple concepts around a common theme, however, can use a single case study type project that extends over the entire semester to develop and link core concepts. A central theme in…

Arguing from evidence is one of eight key science practices in which students should engage. It is an essential component of science, yet students have difficulties with this practice. We describe a scaffolded claims-evidence-reasoning (CER) argumentation framework that is embedded within a new eight-week, freely available curriculum unit…

Many anatomy students begin the course with a misconception that human males and females do not have the same number of ribs. At the root of that misconception is Genesis 2:21-22, in which God removes a rib from Adam to make Eve. Removal of a body part is a surgical procedure, and one does not pass on the results of surgery to one's offspring. The…

Before beginning a series of presentations on evolution, it would be prudent to survey the general level of students' understanding of prerequisite basic concepts of reproduction, heredity, ontology, and phenotypic diversity so that teachers can avoid devoting time to well-known subjects of general knowledge and can spend more time on subjects…

This article discusses a number of aspects of the nature of science that can be illustrated by considering the development of pangenesis, a principle proposed by Charles Darwin to describe the rules of inheritance, explain the source of new variation, and solve other natural history puzzles. Pangenesis--although false--can be used to illustrate…

Epigenetics involves heritable changes in gene expression that do not involve alterations in the DNA sequence. I developed an active-learning approach to convey this topic to students in a college genetics course. I posted a brief summary of the topic before class to stimulate exchange in cooperative groups. During class, we discussed the…

This article presents an activity that uses sandwich bags to represent an individual's genome (their genetic make-up), and two variations of various objects representing the alleles of various genes. This activity includes the major components of an introductory genetics unit: from gamete production through probabilities of expected offspring…

Gregor Mendel (1822-1884) is rightly credited as being the "father of modern genetics." He presented the results of his pea experiments at a meeting of his local natural history society in two lectures during 1865. His paper was published in the proceedings of the society the next year. From his breeding experiments with the edible pea, he…

Evolutionary processes can be studied in nature and in the laboratory, but time and financial constraints result in few opportunities for undergraduate and high school students to explore the agents of genetic change in populations. One alternative to time consuming and expensive teaching laboratories is the use of computer simulations. We…

This lab is a computer simulation of transmission genetics. It presents students with a genetic phenomenon--the inheritance of a randomly--selected trait. The students' task is to determine how this trait is inherited by designing their own crosses and analyzing the results produced by the software.

Probability is an essential tool for understanding heredity and modern genetics, yet many students have difficulty with this topic due to the abstract and quantitative nature of the subject. To facilitate student learning of probability in genetics, we have developed a set of hands-on, cooperative activities that allow students to determine…

A creative learning game that helps students reinforce basic genetic information and facilitate the identification and understanding of the more subtle issues is presented. The basic framework of the game was conceived by a business major taking non-biology major course 'heredity and society-intertwining legacy.

Contends that the natural science curriculum does not prepare biology students for understanding the process of evolution. Proposes improved teaching approaches related to geological time, the natural transition of earth environments, the variability and alteration of genetic makeup, and the biological potential of species as being necessary for…

Examines the content knowledge of genetics as it is organized for solving effect-to-cause problems. Reviews proposed reasons explaining why students find genetics difficult to learn. Explains dominant and codominant inheritance patterns, multiple alleles, and X-linkage. (RT)