Concepts relating to enzymes and energy are central to understanding chemical and biological processes at the molecular level. Student learning of these crosscutting concepts can be challenging, so it is important to identify misconceptions and remediate them early, especially in introductory classes. Here we describe an activity in which…

Exposure to nature can improve mental health and cognitive abilities, while creating enhanced engagement with biological course material through interactions with organisms and ecosystems. Remote biology education was suddenly implemented during the COVID-19 pandemic at many universities, and such distance education continues to provide broadened…

Students need procedural understanding--that is, knowledge of the procedures that scientists use to establish scientific evidence (also known as "concepts of evidence"), to successfully perform scientific investigations, and to evaluate public and scientific claims. However, concepts of evidence are seldom explicitly targeted in routine…

A major challenge in teaching organ development and disease is deconstructing a complex choreography of molecular and cellular changes over time into a linear stepwise process for students. As an entry toward learning developmental concepts, I propose two inexpensive hands-on activities to help facilitate learning of (1) how to identify defects in…

Hands-on learning is a highly effective teaching method for topics in STEM disciplines. Unfortunately, environmental science teachers sometimes lack the tools to engage their students in hands-on experimentation in real-world research outside of the classroom. Partnerships between science professionals and teachers can help address this disparity,…

Undergraduate biology labs often explore the techniques of data collection but neglect the statistical framework necessary to express findings. Students can be confused about how to use their statistical knowledge to address specific biological questions. Growth in the area of observational ecology requires that students gain experience in…

The process of protein translation and translocation into the endoplasmic reticulum (ER) can often be challenging for introductory college biology students to visualize. To help them understand how proteins become oriented in the ER membrane, I developed a hands-on activity in which students use Play-Doh to simulate the process of protein…

We outline protocols for producing slant-minis (SLINIs) and mini-deeps (MEEPs) and examples of their use in simple microbiology experiments suitable for high school students. The principal benefits of these protocols are decreased cost associated with significantly reduced media use; easier, less expensive disposal of waste; and increased safety…

This model-building activity provides a quick, visual, hands-on tool that allows students to examine more carefully the cloverleaf structure of a typical tRNA molecule. When used as a supplement to lessons that involve gene expression, this exercise reinforces several concepts in molecular genetics, including nucleotide base-pairing rules, the…

"Cootie Genetics" is a hands-on, inquiry-based activity that enables students to learn the Mendelian laws of inheritance and gain an understanding of genetics principles and terminology. The activity begins with two true-breeding Cooties of the same species that exhibit five observable trait differences. Students observe the retention or…

Since 1968, biologists have known that termites line up and follow some ballpoint ink lines but not others. Suggestions for class lessons based on this observation have become widespread. However, many of these are incomplete, superficial, conflicting, and/or occasionally inaccurate, and most provide only simple demonstrations or cookbook-style…

Evolutionary theory is the foundation of the biological sciences, yet conveying it to General Biology students often presents a challenge, especially at larger institutions where student numbers in foundation courses can exceed several hundred per lecture section. We present a pedagogically sound exercise that utilizes a series of simple and…

The authors have developed and field-tested high school-level curricular materials that guide students to use biology, mathematics, and physics to understand plankton and how these tiny organisms move in a world where their intuition does not apply. The authors chose plankton as the focus of their materials primarily because the challenges faced…

Describes three models that provide a concrete experience of abstract concepts such as DNA replication, RNA synthesis, and protein synthesis. Explains their hands-on use and notes their advantages for teaching and learning. (JRH)

Laboratory components of introductory biology college-level courses are becoming increasingly rare. Due to the absence of laboratory funding and time, instructors at all levels are faced with the problem of implementing inquiry-based projects. In this article, the authors present an activity that they developed for the 50-minute discussion period…