Objectives: To determine whether hypercholesterolemic adults followed healthy eating and appropriate physical activity. Methods: Using the 2007 Behavioral Risk Factor Surveillance System, we measured greater than or equal to 5 servings of fruits and vegetables/day and "Healthy People 2010" recommended physical activity. Results: Of 363,667 adults greater than or equal to 18 years, 37.3% had hypercholesterolemia. The percentages of healthy eating and physical activity were lower among those with hypercholesterolemia than among those without (23.8% vs 27.9% for healthy eating [P less than 0.001], 43.1% vs 51.7% for physical activity [P less than 0.001]). Conclusion: Hypercholesterolemic adults are less likely to practice healthy eating and to engage in physical activity than are those without hypercholesterolemia.