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Anastasia Dimitropoulos; Ellen A. Doernberg; Rachel A. Gordon; Kerrigan Vargo; Evelyn Nichols; Sandra W. Russ – American Journal on Intellectual and Developmental Disabilities, 2024
The current study examines the efficacy of an 8-week pretend play intervention targeting social-cognitive abilities in children with Prader-Willi syndrome (PWS), ages 6-9. PWS is a rare disorder associated with various social, emotional, and cognitive challenges linked to pretend play impairments, and for which interventions are sparse. Nineteen…
Descriptors: Genetic Disorders, Developmental Disabilities, Obesity, Intellectual Disability
Khemika K. Sudnawa; Wendy K. Chung – American Journal on Intellectual and Developmental Disabilities, 2024
Autism is heterogeneous at many levels, including clinical symptoms and etiology. A key strategy in studying heterogeneous conditions is having large enough sample sizes to stratify into smaller groups that are more homogeneous. SPARK and Simons Searchlight are large and growing research cohorts of individuals with autism in the United States and…
Descriptors: Autism Spectrum Disorders, Research, Data Collection, Genetics
Lisa R. Hamrick; Amanda Seidl; Bridgette L. Kelleher – American Journal on Intellectual and Developmental Disabilities, 2023
Automated methods for processing of daylong audio recordings are efficient and may be an effective way of assessing developmental stage for typically developing children; however, their utility for children with developmental disabilities may be limited by constraints of algorithms and the scope of variables produced. Here, we present a novel…
Descriptors: Genetic Disorders, Developmental Disabilities, Child Development, Verbal Communication
Maltman, Nell; DaWalt, Leeann Smith; Hong, Jinkuk; Baker, Mei Wang; Berry-Kravis, Elizabeth M.; Brilliant, Murray H.; Mailick, Marsha – American Journal on Intellectual and Developmental Disabilities, 2023
Variation in the "FMR1" gene may affect aspects of cognition, such as executive function and memory. Environmental factors, such as stress, may also negatively impact cognitive functioning. Participants included 1,053 mothers of children with and without developmental disabilities. Participants completed self-report measures of executive…
Descriptors: Genetics, Cognitive Ability, Executive Function, Memory
Berry-Kravis, Elizabeth – American Journal on Intellectual and Developmental Disabilities, 2022
Fragile X syndrome (FXS), as a monogenic cause of intellectual disability and autism spectrum disorder, has been one of the first neurodevelopmental disorders in which molecular and neuronal mechanisms of disease have been identified, leading to the concept of targeting the underlying disease to reverse symptoms. Translating findings in basic…
Descriptors: Genetic Disorders, Intellectual Disability, Autism, Pervasive Developmental Disorders
Wilkinson, Ellen H.; Britton, Tobias C.; Hall, Scott S. – American Journal on Intellectual and Developmental Disabilities, 2022
We examined potential phenotypic differences in eye gaze avoidance exhibited by boys with autism spectrum disorder (ASD) and boys with fragile X syndrome (FXS). In Study 1, the Eye Contact Avoidance Scale (ECAS) was administered to caregivers of boys aged 7-18 years with FXS (n = 148), ASD (n = 168), and mixed developmental disabilities (MDD; n =…
Descriptors: Autism Spectrum Disorders, Genetic Disorders, Eye Movements, Males
Smith, Kayla; Hogan, Abigail L.; Will, Elizabeth; Roberts, Jane E. – American Journal on Intellectual and Developmental Disabilities, 2021
Early identification of behavioral risk markers for anxiety is essential to optimize long-term outcomes in children with neurodevelopmental disorders. This study analyzed attentional avoidance and its relation to anxiety and autism spectrum disorder (ASD) symptomatology during social and nonsocial fear conditions in toddlers with fragile X…
Descriptors: Disability Identification, At Risk Persons, Anxiety, Neurological Impairments
Britton, Tobias C.; Wilkinson, Ellen H.; Hall, Scott S. – American Journal on Intellectual and Developmental Disabilities, 2020
Limited information is available concerning the specificity of the forms and functions of aggressive behavior exhibited by boys with fragile X syndrome (FXS). To investigate these relationships, we conducted indirect functional assessments of aggressive behavior exhibited by 41 adolescent boys with FXS and 59 age and symptom-matched controls with…
Descriptors: Aggression, Males, Genetic Disorders, Adolescents
Harrop, Clare; Dallman, Aaron R.; Lecavalier, Luc; Bodfish, James W.; Boyd, Brian A. – American Journal on Intellectual and Developmental Disabilities, 2021
Behavioral inflexibility (BI) has been highlighted to occur across genetic and neurodevelopmental disorders. This study characterized BI in two common neurogenetic conditions: Fragile X syndrome (FXS) and Down syndrome (DS). Caregivers of children with FXS (N = 56; with ASD = 28; FXS only = 28) and DS (N = 146) completed the Behavioral…
Descriptors: Down Syndrome, Genetic Disorders, Neurological Impairments, Developmental Disabilities
Zyga, Olena; Dimitropoulos, Anastasia – American Journal on Intellectual and Developmental Disabilities, 2020
Early parent-child interactions (PCI) impact social cognitive development. Relatedly, children with various developmental disorders exhibit abnormal parental attachment relationships. Parental characteristics and behaviors can impact PCI and socioemotional development as well. No research has examined the parent-child dynamic in Prader-Willi…
Descriptors: Preschool Children, Parent Child Relationship, Genetic Disorders, Stress Variables
Hahn, Laura J.; Fidler, Deborah J.; Hepburn, Susan L. – American Journal on Intellectual and Developmental Disabilities, 2014
The present study compares the adaptive behavior profile of 18 young children with Williams syndrome (WS) and a developmentally matched group of 19 children with developmental disabilities and examines the relationship between adaptive behavior and problem behaviors in WS. Parents completed the Vineland Adaptive Behavioral Scales--Interview…
Descriptors: Genetic Disorders, Behavior Problems, Young Children, Comparative Analysis
Byiers, Breanne J.; Dimian, Adele; Symons, Frank J. – American Journal on Intellectual and Developmental Disabilities, 2014
Rett syndrome (RTT) is associated with a range of serious neurodevelopmental consequences including severe communicative impairments. Currently, no evidence-based communication interventions exist for the population (Sigafoos et al., 2009). The purpose of the current study was to examine the effectiveness of functional assessment (FA) and…
Descriptors: Genetic Disorders, Neurological Impairments, Developmental Disabilities, Communication Problems
Sterling, Audra M.; Warren, Steven F.; Brady, Nancy; Fleming, Kandace – American Journal on Intellectual and Developmental Disabilities, 2013
This study investigated the influence of maternal and child variables on the maternal responsivity of 55 mothers with young children with fragile X syndrome. Data included video observations of mother-child interactions in four different contexts, standardized assessments with the children, and standardized questionnaires for the mothers. The…
Descriptors: Genetic Disorders, Mothers, Young Children, Observation
Shashi, Vandana; Wray, Emily; Schoch, Kelly; Curtiss, Kathleen; Hooper, Stephen R. – American Journal on Intellectual and Developmental Disabilities, 2013
Children with 22q11.2 deletion syndrome exhibit high rates of social-behavioral problems, particularly in the internalizing domain, indicating an area in need of intervention. The current investigation was designed to obtain information regarding parent and teacher ratings of the social-emotional behavior of children with 22q11DS. Using the Child…
Descriptors: Genetic Disorders, Behavior Problems, Intervention, Social Behavior
Kover, Sara T.; Atwood, Amy K. – American Journal on Intellectual and Developmental Disabilities, 2013
This methodological review draws attention to the challenges faced by intellectual and developmental disabilities researchers in the appropriate design and analysis of group comparison studies. We provide a brief overview of matching methodologies in the field, emphasizing group-matching designs used in behavioral research on cognition and…
Descriptors: Research Methodology, Research Design, Behavioral Science Research, Comparative Analysis
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