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Direct linkRachidi, Mohammed; Lopes, Carmela – American Journal on Intellectual and Developmental Disabilities, 2010
Down syndrome, the most common genetic cause of intellectual disability, is associated with brain disorders due to chromosome 21 gene overdosage. Molecular and cellular mechanisms involved in the neuromorphological alterations and cognitive impairments are reported herein in a global model. Recent advances in Down syndrome research have lead to…
Descriptors: Down Syndrome, Pathology, Mental Retardation, Molecular Structure
