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Comparison of Case-Based Learning and Traditional Teaching Methods in Advanced Breast Cancer Education for Oncology Residents in the Standardized Training
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Xinyu Gui; Anjie Zhu; Guohong Song; Huiping Li – Biochemistry and Molecular Biology Education, 2025
Case-based learning (CBL) is a learner-centric educational approach that fosters independent learning and exploration through case analysis, guided by teachers' heuristic instruction. The study aimed to evaluate the efficacy of CBL versus traditional teaching methods in advanced breast cancer education for residents. In this randomized controlled…
Descriptors: Cancer, Biochemistry, Science Instruction, Thinking Skills
Problem-Solving Test: Analysis of DNA Damage Recognizing Proteins in Yeast and Human Cells
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Szeberenyi, Jozsef – Biochemistry and Molecular Biology Education, 2013
The experiment described in this test was aimed at identifying DNA repair proteins in human and yeast cells. Terms to be familiar with before you start to solve the test: DNA repair, germline mutation, somatic mutation, inherited disease, cancer, restriction endonuclease, radioactive labeling, [alpha-[superscript 32]P]ATP, [gamma-[superscript…
Descriptors: Genetics, Science Experiments, Multiple Choice Tests, Problem Solving
Problem-Solving Test: The Role of a Micro-RNA in the Regulation of "fos" Gene Expression
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Szeberenyi, Jozsef – Biochemistry and Molecular Biology Education, 2009
The "fos" proto-oncogene codes for a component of the AP1 transcription factor, an important regulator of gene expression and cell proliferation. Dysregulation of AP1 function may lead to the malignant transformation of the cell. The present test describes an experiment in which the role of a micro-RNA (miR-7b) in the regulation of "fos" gene…
Descriptors: Genetics, Cancer, Role, Molecular Biology
Problem-Solving Test: Real-Time Polymerase Chain Reaction
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Szeberenyi, Jozsef – Biochemistry and Molecular Biology Education, 2009
Terms to be familiar with before you start to solve the test: polymerase chain reaction, DNA amplification, electrophoresis, breast cancer, "HER2" gene, genomic DNA, "in vitro" DNA synthesis, template, primer, Taq polymerase, 5[prime][right arrow]3[prime] elongation activity, 5[prime][right arrow]3[prime] exonuclease activity, deoxyribonucleoside…
Descriptors: Cancer, Chemistry, Genetics, Molecular Biology
Problem-Solving Test: The Mechanism of Action of a Human Papilloma Virus Oncoprotein
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Szeberenyi, Jozsef – Biochemistry and Molecular Biology Education, 2009
Terms to be familiar with before you start to solve the test: human papilloma virus; cervical cancer; oncoproteins; malignant transformation; retinoblastoma protein; cell cycle; quiescent and cycling cells; cyclin/cyclin-dependent kinase (Cdk) complexes; E2F; S-phase genes; enhancer element; proto-oncogenes; tumor suppressor genes; radioactive…
Descriptors: Cancer, Genetics, Science Tests, Problem Solving
Experimental Approaches to Microarray Analysis of Tumor Samples
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Furge, Laura Lowe; Winter, Michael B.; Meyers, Jacob I.; Furge, Kyle A. – Biochemistry and Molecular Biology Education, 2008
Comprehensive measurement of gene expression using high-density nucleic acid arrays (i.e. microarrays) has become an important tool for investigating the molecular differences in clinical and research samples. Consequently, inclusion of discussion in biochemistry, molecular biology, or other appropriate courses of microarray technologies has…
Descriptors: Measurement Techniques, Diseases, Cancer, Science Instruction