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Draganski, Bogdan; Martino, Davide; Cavanna, Andrea E.; Hutton, Chloe; Orth, Michael; Robertson, Mary M.; Critchley, Hugo D.; Frackowiak, Richard S. – Brain, 2010
Tourette syndrome is a childhood-onset neuropsychiatric disorder with a high prevalence of attention deficit hyperactivity and obsessive-compulsive disorder co-morbidities. Structural changes have been found in frontal cortex and striatum in children and adolescents. A limited number of morphometric studies in Tourette syndrome persisting into…
Descriptors: Attention Deficit Hyperactivity Disorder, Integrity, Patients, Brain
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Fallet-Bianco, Catherine; Loeuillet, Laurence; Poirier, Karine; Loget, Philippe; Chapon, Francoise; Pasquier, Laurent; Saillour, Yoann; Beldjord, Cherif; Chelly, Jamel; Francis, Fiona – Brain, 2008
Lissencephalies are congenital malformations responsible for epilepsy and mental retardation in children. A number of distinct lissencephaly syndromes have been characterized, according to the aspect and the topography of the cortical malformation, the involvement of other cerebral structures and the identified genetic defect. A mutation in…
Descriptors: Congenital Impairments, Genetic Disorders, Animals, Behavior Disorders