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Direct linkMoritz, Steffen; Jelinek, Lena; Hottenrott, Birgit; Klinge, Ruth; Randjbar, Sarah – Brain and Cognition, 2009
Recent neuroimaging studies have consistently ascribed the orbito-frontal cortex (OFC) a pivotal role in the pathogenesis of obsessive-compulsive disorder (OCD). Cognitive tests presumed sensitive to this region, such as the Object Alternation Task (OAT), are considered important tools to verify this assumption and to investigate the impact of…
Descriptors: Cognitive Tests, Pathology, Patients, Depression (Psychology)
Evans, David W.; Lewis, Marc D.; Iobst, Emily – Brain and Cognition, 2004
Mounting evidence concerning obsessive-compulsive disorders points to abnormal functioning of the orbitofrontal cortices. First, patients with obsessive-compulsive disorder (OCD) perform poorly on tasks that rely on response suppression/motor inhibition functions mediated by the orbitofrontal cortex relative to both normal and clinical controls.…
Descriptors: Brain, Behavior Disorders, Behavior Standards, Patients
