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Castner, Stacy A.; Williams, Graham V. – Brain and Cognition, 2007
The prefrontal cortex of the primate frontal lobes provides the capacity for judgment which can constantly adapt behavior in order to optimize its outcome. Adjudicating between long-term memory programs and prepotent responses, this capacity reviews all incoming information and provides an interpretation dependent on the events that have just…
Descriptors: Brain Hemisphere Functions, Schemata (Cognition), Schizophrenia, Long Term Memory
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Clark, L.; Cools, R.; Robbins, T. W. – Brain and Cognition, 2004
Converging evidence from human lesion, animal lesion, and human functional neuroimaging studies implicates overlapping neural circuitry in ventral prefrontal cortex in decision-making and reversal learning. The ascending 5-HT and dopamine neurotransmitter systems have a modulatory role in both processes. There is accumulating evidence that…
Descriptors: Brain, Neuropsychology, Decision Making, Learning Processes