Many patients with primary progressive aphasia (PPA) are impaired in syntactic production. Because most previous studies of expressive syntax in PPA have relied on quantitative analysis of connected speech samples, which is a relatively unconstrained task, it is not well understood which specific syntactic structures are most challenging for these…

Patients with primary progressive aphasia (PPA) vary considerably in terms of which brain regions are impacted, as well as in the extent to which syntactic processing is impaired. Here we review the literature on the neural basis of syntactic deficits in PPA. Structural and functional imaging studies have most consistently associated syntactic…

Patients with damage involving left ventrolateral prefrontal cortex (left VLPFC) often show syntactic deficits. They also show exaggerated interference effects during a variety of non-syntactic tasks, including picture naming and working memory. Conceivably, both deficits could arise from inadequate biasing of competitive interactions during…

Purpose: Bilingual aphasia generally affects both languages. However, the age of acquisition of the second language (L2) seems to play a role in the anatomo-functional correlation of the syntactical/grammatical processes, thus potentially influencing the L2 syntactic impairment following a stroke. The present study aims to analyze the influence of…

In order to explore the impact of a degraded semantic system on the structure of language production, we analysed transcripts from autobiographical memory interviews to identify naturally-occurring speech errors by eight patients with semantic dementia (SD) and eight age-matched normal speakers. Relative to controls, patients were significantly…

This paper presents the results of a study of the effects of left hemisphere strokes on syntactically-based comprehension in aphasic patients. We studied 42 patients with aphasia secondary to left hemisphere strokes and 25 control subjects for the ability to assign and interpret three syntactic structures (passives, object extracted relative…

Despite the increasing number of neuroimaging studies of syntactic gender processing no model is currently available that includes data from visual and auditory language comprehension and language production. This paper provides a systematic review of the neural correlates of syntactic gender processing. Based on anatomical information from…

This paper presents the results of a study of syntactically based comprehension in aphasic patients. We studied 42 patients with aphasia secondary to left hemisphere strokes and 25 control participants. We measured off-line, end-of-sentence, performance (accuracy and reaction time) in two tasks that require comprehension--enactment and…

We report on three experiments that provide a real-time processing perspective on the poor comprehension of Broca's aphasic patients for non-canonically structured sentences. In the first experiment we presented sentences (via a Cross Modal Lexical Priming (CMLP) paradigm) to Broca's patients at a normal rate of speech. Unlike the pattern found…

We reanalyzed the data in Drai and Grodzinksy (2005), considering individual patients' responses to different sentence types to be non-independent events. The analyses revealed effects of two of the three factors identified by Drai and Grodzinsky-constituent movement and passive mood. The result is inconsistent with the trace deletion hypothesis;…

Behavioral variation in Broca's aphasia has been characterized as boundless, calling into question the validity of the syndrome-based schema and related diagnostic methods of acquired language disorders. More generally, this putative variability has cast serious doubts on the feasibility of localizing linguistic operations in cortex. We present a…

This study examines the comprehension patterns of various sentence types by Mandarin-speaking aphasic patients and evaluates the validity of the predictions from the Trace-Deletion Hypothesis (TDH) and the Double Dependency Hypothesis (DDH). Like English, the canonical word order in Mandarin is SVO, but the two languages differ in that the head…

Hierarchical models of agrammatism propose that sentence production deficits can be accounted for in terms of clausal syntactic structure [Friedmann, N., & Grodzinsky, Y. (1997). "Tense and agreement in agrammatic production: Pruning the syntactic tree." "Brain and Language, 56", 397-425; Hagiwara, H. (1995). "The breakdown of functional…

In this paper, we investigate the performance of a Greek-English bilingual patient with Broca's aphasia and mild agrammatism on the placement of CP, MoodP, AspectP, and NegP-related adverbs, labeled specifier-type adverbs, and VP-related adverbs, labeled complement-type adverbs, by means of a constituent ordering task and a grammaticality judgment…

We respond to critical comments and consider alternative statistical and syntactic analyses of our target paper which analyzed comprehension scores of Broca's aphasic patients from multiple sentence types in many languages, and showed that Movement but not Complexity or Mood are factors in the receptive deficit of these patients. Specifically, we…